ArticleClinical and experimental immunology1992
T cell regulation of the chronic peritoneal neutrophilia during mycobacterial infections.
Article in Clinical and experimental immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Sera from patients with active pulmonary tuberculosis and their household contacts induce nuclear changes in neutrophils.Infection and drug resistance · 2018Article
- Lymphocytes modulate peritoneal leukocyte recruitment in peritonitis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2009Article
- Defects in actin dynamics lead to an autoinflammatory condition through the upregulation of CXCL5.PloS one · 2008Article
- Neutrophil responses to Mycobacterium tuberculosis infection in genetically susceptible and resistant mice.Infection and immunity · 2005Article
- Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice.Infection and immunity · 2000Article
- Susceptibility of beige mice to Mycobacterium avium: role of neutrophils.Infection and immunity · 1995Article
- Inflammatory response following intranasal infection with Mycobacterium avium complex: role of T-cell subsets and gamma interferon.Infection and immunity · 1995Article
- The role of lymphocytes in the neutrophil migration induced by ovalbumin in immunized rats.Immunology · 1995Article
- Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis.Immunology · 1994Article
- Altered expression of CD11/CD18 on the peripheral blood phagocytes of patients with tuberculosis.Clinical and experimental immunology · 1994Article
- Interferon-gamma (IFN-gamma) and macrophage inflammatory proteins (MIP)-1 and -2 are involved in the regulation of the T cell-dependent chronic peritoneal neutrophilia of mice infected with mycobacteria.Clinical and experimental immunology · 1992Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intraperitoneal infection of mice with mycobacteria induces the persistent mobilization of neutrophils to the infected peritoneal cavities. The recruitment of the neutrophils was mediated by the immune system since it was enhanced by immunization and reduced in T cell-deficient nude and SCID mice. Anti-mitotic treatments with cyclophosphamide or X-rays led to a reduction in the number of mononuclear cells in the peritoneal cavity of infected mice, followed by a reduction in neutrophil numbers despite the presence of a normal circulating pool of neutrophils. The depletion of T cells with antibodies during mycobacterial i.p. infection led to a reduction in the number of neutrophils. Such a reduction was more extensive if the antibodies were administered early. Our data suggest that T cells are partially involved in the direct recruitment of neutrophils during chronic mycobacteriosis but they also play a role in the priming of other cell types for the mobilization of these phagocytes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.