Evidence map›Paper›PMID 16283401›Full record

Trial reportExperimental brain research2005

Training BIG to move faster: the application of the speed-amplitude relation as a rehabilitation strategy for people with Parkinson's disease.

Becky G Farley, Gail F Koshland

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Experimental brain research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03602443 (Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke), which is not on this map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03602443 nacompletednot on this mapstarted 2018, after this paper: background citation

Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2018 to 2019Enrolled5ConditionsChronic StrokeArmsLSVT®BIG Intervention, Waitlist Control
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Becky G FarleyDepartment of Physiology, University of Arizona, Tucson, AZ 85724, USA. bfarley@u.arizona.edu
Gail F Koshland

Funding

Think big, from voice to limb movement rehabilitationR21NS043711 · NINDS · UNIVERSITY OF ARIZONA · PI FARLEY, BECKY G · 2003 to 2004
$351k
NINDS NIH HHS R21 NS043711-04A1
6 · The paper itself

Abstract

We have used the phenomenon that speed increases with movement amplitude as a rehabilitation strategy. We tested the hypothesis that the generalized training of amplitude in the limb motor system may reduce bradykinesia and hypokinesia in the upper and lower limbs in subjects with Parkinson's disease (PD) across disease severity (Stage I, n=6; Stage II, n=7; Stage III, n=5). While studies have separately examined the relationship of amplitude to speed in reaching and gait, the same study has not reported the relationship for both limb systems. Moreover, the rehabilitation intervention, Training BIG, is unique in that it applies well-established treatment concepts from a proven treatment for the speech motor system in PD [Lee Silverman Voice Treatment (LSVT)] to the limb motor system. Subjects (n=18) participated in intense practice (1-h sessions/4x week/4 weeks) of large amplitude movements involving the whole body (i.e., head, arm, trunk, and leg) while focusing on the sensory awareness of "movement bigness." Testing procedures were designed to demonstrate the transfer of generalized amplitude practice to speed improvements during functional "untrained" tasks in "uncued" conditions with blinded testers. After therapy, the subjects significantly increased their speed of reaching and gait for the preferred speed condition. This effect was greater when the severity of the disease was less. The results support further application and efficacy studies of Training BIG. Amplitude-based behavioral intervention in people with PD appears to be a simple target that may be applied in different contexts for multiple tasks and results in improved speed-amplitude scaling relations across the upper and lower limbs.

Indexed as

AgedArmFemaleGaitHead MovementsHumansLegMaleMovementParkinson DiseasePhysical Therapy ModalitiesPsychomotor PerformanceThoraxWalking

Identifiers

PMID16283401

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.