ArticleBMJ (Clinical research ed.)2005
Cost effectiveness analysis of strategies for maternal and neonatal health in developing countries.
Article in BMJ (Clinical research ed.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 19 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
145 citing papers in PubMed, 19 syntheses or guidelines pooled it, 368 citations in OpenAlex.
- How are maternal and fetal outcomes incorporated when measuring benefits of interventions in pregnancy? Findings from a systematic review of cost-utility analyses.Health and quality of life outcomes · 2024Pooled it
- A Systematic Review of Methods and Practice for Integrating Maternal, Fetal, and Child Health Outcomes, and Family Spillover Effects into Cost-Utility Analyses.PharmacoEconomics · 2024Pooled it
- Effect of antenatal care on low birth weight: a systematic review and meta-analysis in Africa, 2022.Frontiers in public health · 2023Pooled it
- Economic Evaluations of Child Nutrition Interventions in Low- and Middle-Income Countries: Systematic Review and Quality Appraisal.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- The effect of antenatal care on perinatal outcomes in Ethiopia: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Effectiveness and cost-effectiveness of home-based postpartum care on neonatal mortality and exclusive breastfeeding practice in low-and-middle-income countries: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2019Pooled it
- A Systematic Review of Orthopedic Global Outreach Efforts Based on WHO-CHOICE Thresholds.Hand clinics · 2019Pooled it
- The impact of antenatal care on neonatal mortality in sub-Saharan Africa: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Using Economic Evidence to Set Healthcare Priorities in Low-Income and Lower-Middle-Income Countries: A Systematic Review of Methodological Frameworks.Health economics · 2016Pooled it
- Factors influencing breastfeeding exclusivity during the first 6 months of life in developing countries: a quantitative and qualitative systematic review.Maternal & child nutrition · 2015Pooled it
- Facilitators and barriers to facility-based delivery in low- and middle-income countries: a qualitative evidence synthesis.Reproductive health · 2014Pooled it
- Cost-effectiveness of strategies to improve the utilization and provision of maternal and newborn health care in low-income and lower-middle-income countries: a systematic review.BMC pregnancy and childbirth · 2014Pooled it
- Cost-effectiveness of surgery in low- and middle-income countries: a systematic review.World journal of surgery · 2014Pooled it
- The effect of health facility delivery on neonatal mortality: systematic review and meta-analysis.BMC pregnancy and childbirth · 2013Pooled it
- The state of health economic research in South Africa: a systematic review.PharmacoEconomics · 2012Pooled it
- Quantifying the fall in mortality associated with interventions related to hypertensive diseases of pregnancy.BMC public health · 2011Pooled it
- Different antibiotic regimens for treating asymptomatic bacteriuria in pregnancy.The Cochrane database of systematic reviews · 2010Pooled it
- 60 Million non-facility births: who can deliver in community settings to reduce intrapartum-related deaths?International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2009Pooled it
- A systematic review of inequalities in the use of maternal health care in developing countries: examining the scale of the problem and the importance of context.Bulletin of the World Health Organization · 2007Pooled it
- Exploring the effect of implementation and context on a stepped-wedge randomised controlled trial of a vital sign triage device in routine maternity care in low-resource settings.Implementation science : IS · 2019Trial
85 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the costs and benefits of interventions for maternal and newborn health to assess the appropriateness of current strategies and guide future plans to attain the millennium development goals.
designCost effectiveness analysis.
settingTwo regions classified by the World Health Organization according to their epidemiological grouping: Afr-E, those countries in sub-Saharan Africa with very high adult and high child mortality, and Sear-D, comprising countries in South East Asia with high adult and high child mortality. DATA SOURCES: Effectiveness data from several sources, including trials, observational studies, and expert opinion. For resource inputs, quantities came from WHO guidelines, literature, and expert opinion, and prices from the WHO choosing interventions that are cost effective database.
main outcome measuresCost per disability adjusted life year (DALY) averted in year 2000 international dollars.
resultsThe most cost effective mix of interventions was similar in Afr-E and Sear-D. These were the community based newborn care package, followed by antenatal care (tetanus toxoid, screening for pre-eclampsia, screening and treatment of asymptomatic bacteriuria and syphilis); skilled attendance at birth, offering first level maternal and neonatal care around childbirth; and emergency obstetric and neonatal care around and after birth. Screening and treatment of maternal syphilis, community based management of neonatal pneumonia, and steroids given during the antenatal period were relatively less cost effective in Sear-D. Scaling up all of the included interventions to 95% coverage would halve neonatal and maternal deaths.
conclusionPreventive interventions at the community level for newborn babies and at the primary care level for mothers and newborn babies are extremely cost effective, but the millennium development goals for maternal and child health will not be achieved without universal access to clinical services as well.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.