ArticleEukaryotic cell2005
Comparison of cell wall localization among Pir family proteins and functional dissection of the region required for cell wall binding and bud scar recruitment of Pir1p.
Article in Eukaryotic cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 43 citations in OpenAlex.
- The secretorymLife · 2023Article
- Peering IntoFrontiers in cellular and infection microbiology · 2022Article
- The Saccharomyces cerevisiae Ncw2 protein works on the chitin/β-glucan organisation of the cell wall.Antonie van Leeuwenhoek · 2021Article
- A Differential Proteomic Approach to Characterize the Cell Wall Adaptive Response to COMicroorganisms · 2020Article
- Simultaneous Nanoscale Imaging of Chemical and Architectural Heterogeneity on Yeast Cell Wall Particles.Langmuir : the ACS journal of surfaces and colloids · 2020Article
- Phenotypic Variability in a Coinfection With Three IndependentFrontiers in microbiology · 2020Article
- Partner Choice in Spontaneous Mitotic Recombination in Wild Type and Homologous Recombination Mutants ofG3 (Bethesda, Md.) · 2019Article
- Biological Roles of Protein-Coding Tandem Repeats in the YeastJournal of fungi (Basel, Switzerland) · 2018Article
- Article
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- Unexpected role for a serine/threonine-rich domain in the Candida albicans Iff protein family.Eukaryotic cell · 2011Article
- Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody.Microbiology (Reading, England) · 2010Article
- Impact of genetic background on allele selection in a highly mutable Candida albicans gene, PNG2.PloS one · 2010Article
- Construction of a novel Pichia pastoris cell-surface display system based on the cell wall protein Pir1.Current microbiology · 2008Article
- The cytoplasmic region of alpha-1,6-mannosyltransferase Mnn9p is crucial for retrograde transport from the Golgi apparatus to the endoplasmic reticulum in Saccharomyces cerevisiae.Eukaryotic cell · 2008Article
- Construction of a library of human glycosyltransferases immobilized in the cell wall of Saccharomyces cerevisiae.Applied and environmental microbiology · 2006Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined the localization of the Pir protein family (Pir1 to Pir4), which is covalently linked to the cell wall in an unknown manner. In contrast to the other Pir proteins, a fusion of Pir1p and monomeric red fluorescent protein distributed in clusters in pir1Delta cells throughout the period of cultivation, indicating that Pir1p is localized in bud scars. Further microscopic analysis revealed that Pir1p is expressed inside the chitin rings of the bud scars. Stepwise deletion of the eight units of the repetitive sequence of Pir1p revealed that one unit is enough for the protein to bind bud scars and that the extent of binding of Pir1p to the cell wall depends on the number of these repetitive units. The localization of a chimeric Pir1p in which the repetitive sequence of Pir1p was replaced with that of Pir4p revealed the functional role of the different protein regions, specifically, that the repetitive sequence is required for binding to the cell wall and that the C-terminal sequence is needed for recruitment to bud scars. This is the first report that bud scars contain proteins like Pir1p as internal components.
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