ArticleGenome biology2005
A computational investigation of kinetoplastid trans-splicing.
Article in Genome biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Structural analysis of PpSP15 and PsSP9 sand fly salivary proteins designed with a self-cleavable linker as a live vaccine candidate against cutaneous leishmaniasis.Parasites & vectors · 2022Article
- SLFinder, a pipeline for the novel identification of splice-leader sequences: a good enough solution for a complex problem.BMC bioinformatics · 2020Article
- Evolution of Alternative Splicing in Eudicots.Frontiers in plant science · 2019Article
- UTRme: A Scoring-Based Tool to Annotate Untranslated Regions in Trypanosomatid Genomes.Frontiers in genetics · 2018Article
- Programmed Genome Rearrangements in the Ciliate Oxytricha.Microbiology spectrum · 2014Review
- SLaP mapper: a webserver for identifying and quantifying spliced-leader addition and polyadenylation site usage in kinetoplastid genomes.Molecular and biochemical parasitology · 2014Article
- The calmodulin intergenic spacer as molecular target for characterization of Leishmania species.Parasites & vectors · 2014Article
- "Eco-omics": a review of the application of genomics, transcriptomics, and proteomics for the study of the ecology of harmful algae.Microbial ecology · 2013Review
- Genomic organization of leishmania species.Iranian journal of parasitology · 2011Article
- Article
- The transcriptome of the human pathogen Trypanosoma brucei at single-nucleotide resolution.PLoS pathogens · 2010Article
- Transgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes.Molecular & cellular proteomics : MCP · 2008Article
- Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania.BMC bioinformatics · 2008Article
- Codon usage suggests that translational selection has a major impact on protein expression in trypanosomatids.BMC genomics · 2008Article
- Article
- Spliced leader RNA trans-splicing in dinoflagellates.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Mapping the antigenicity of the parasites in Leishmania donovani infection by proteome serology.PloS one · 2006Article
- Correction: genetic algorithm learning as a robust approach to RNA editing site site prediction.BMC bioinformatics · 2006Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trans-splicing is an unusual process in which two separate RNA strands are spliced together to yield a mature mRNA. We present a novel computational approach which has an overall accuracy of 82% and can predict 92% of known trans-splicing sites. We have applied our method to chromosomes 1 and 3 of Leishmania major, with high-confidence predictions for 85% and 88% of annotated genes respectively. We suggest some extensions of our method to other systems.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.