Evidence map›Paper›PMID 16277348›Full record

ArticleThe Journal of organic chemistry2005

Synthesis of double C-glycoside analogue of sTn.

Dino K Ress, Sultan N Baytas, Qun Wang, Eva M Muñoz, Kazuo Tokuzoki, Hiroshi Tomiyama, Robert J Linhardt

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dino K RessDepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
Sultan N Baytas
Qun Wang
Eva M Muñoz
Kazuo Tokuzoki
Hiroshi Tomiyama
Robert J Linhardt
Rensselaer Polytechnic Institute · USUniversity of Iowa · US

Funding

Stable Carbohydrate Libraries in Infectious DiseaseR01AI065786 · NIAID · RENSSELAER POLYTECHNIC INSTITUTE · PI LINHARDT, ROBERT J · 2007 to 2011
$1.9M
NIAID NIH HHS R01 AI065786
6 · The paper itself

Abstract

A sTn double C-glycoside, sTn analogue 2, was synthesized using samarium chemistry developed in our laboratory. Complications in the oxidation reaction affording aldehyde acceptor were overcome by double protection of amide and the use of a room-temperature ionic liquid as solvent. Studies are underway to conjugate the sTn double C-glycoside hapten 2 to KLH carrier protein for biological evaluation as a vaccine.

Indexed as

Sialic AcidsTinCarbohydrate ConformationDisaccharidesGlycosidesIndicators and ReagentsMagnetic Resonance SpectroscopyModels, MolecularMolecular StructureNeuraminic AcidsDisaccharidesGlycosidesIndicators and ReagentsNeuraminic AcidsSialic AcidsTin

Identifiers

PMID16277348
PMCPMC4112365
OpenAlexW2058786043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.