ReviewThe Journal of clinical investigation2005
CD36 may determine our desire for dietary fats.
Review in The Journal of clinical investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 81 citations in OpenAlex.
- Chlorogenic acid inhibits intestinal lipid uptake and promotes adipose lipid catabolism via epithelium-derived exosomes in ob/ob mice.Frontiers in physiology · 2026Article
- Fat malabsorption in short bowel syndrome: A review of pathophysiology and management.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024Review
- Genetic Variants inNutrients · 2023Article
- Understanding across the senses: cross-modal studies of cognition in cetaceans.Animal cognition · 2022Review
- Amentoflavone-EnrichedLife (Basel, Switzerland) · 2022Article
- GPR84 Is Essential for the Taste of Medium Chain Saturated Fatty Acids.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Soluble Receptors Affecting Stroke Outcomes: Potential Biomarkers and Therapeutic Tools.International journal of molecular sciences · 2021Review
- Transection of Gustatory Nerves Differentially Affects Dietary Fat Intake in Obesity-Prone and Obesity-Resistant Rats.Chemical senses · 2020Article
- Studies of human twins reveal genetic variation that affects dietary fat perception.Chemical senses · 2020Article
- Blood-Related Toxicity after Traumatic Brain Injury: Potential Targets for Neuroprotection.Molecular neurobiology · 2020Review
- Brain Imaging of Taste Perception in Obesity: a Review.Current nutrition reports · 2019Review
- Idiopathic Chyluria with Nephrotic-range Proteinuria and Hypothyroidism.Internal medicine (Tokyo, Japan) · 2019Article
- Elevated CD36 expression correlates with increased visceral adipose tissue and predicts poor prognosis in ccRCC patients.Journal of Cancer · 2019Article
- Lingual CD36 and nutritional status differentially regulate fat preference in obesity-prone and obesity-resistant rats.Physiology & behavior · 2017Article
- Iso-α-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease.The Journal of biological chemistry · 2017Article
- ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2016Article
- Recent advances in the modification of taste and food preferences following bariatric surgery.Reviews in endocrine & metabolic disorders · 2016Review
- Fat sensing and metabolic syndrome.Reviews in endocrine & metabolic disorders · 2014Review
- CD36- and GPR120-mediated Ca²⁺ signaling in human taste bud cells mediates differential responses to fatty acids and is altered in obese mice.Gastroenterology · 2014Article
- Preference for linoleic acid in obesity-prone and obesity-resistant rats is attenuated by the reduction of CD36 on the tongue.American journal of physiology. Regulatory, integrative and comparative physiology · 2013Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is a strong link between high fat intake and obesity. In addition to its high caloric density, dietary fat has a hyperphagic effect, in part as a result of its high palatability. The recent identification by Laugerette et al. of CD36 as a taste receptor for fatty acids provides insight into the molecular basis of our preference for fat (see the related article beginning on page 3177). As we gain more information regarding the function of this receptor, we may be able to devise better strategies to address the addictive potential of dietary fat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.