Evidence map›Paper›PMID 16275498›Full record

SynthesisBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2005

Chronomics affirm extending scope of lead in phase of duodenal vs. pineal circadian melatonin rhythms.

B Poeggeler, G Cornélissen, G Huether, R Hardeland, R Józsa, M Zeman, K Stebelova, A Oláh, G Bubenik, W Pan and 4 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Extrapineal melatonin: sources, regulation, and potential functions.Cellular and molecular life sciences : CMLS · 2014
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Chronomics reveal and quantify circadian rhythmic melatonin in duodenum of rats.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

B PoeggelerInstitute of Zoology, Anthropology and Developmental Biology, University of Göttingen, Göttingen, Germany.
G Cornélissen
G Huether
R Hardeland
R Józsa
M Zeman
K Stebelova
A Oláh
G Bubenik
W Pan
K Otsuka
O Schwartzkopff
E E Bakken
F Halberg

Funding

TIMING OF PHYSIOLOGIC FUNCTIONS IN HEALTH AND DISEASEK06GM013981 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HALBERG, FRANZ · 1985 to 2012
$424k
NIGMS NIH HHS K06 GM013981
6 · The paper itself

Abstract

In Göttingen, Germany, circadian variations in melatonin had been determined time-macroscopically in pineal glands, blood plasma and duodenum of chicken and rats. When these data were meta-analyzed, they agreed with the results from an independent survey on tissues from rats collected in a laboratory in Pécs, Hungary. In the latter study, tissues were analyzed chemically in Bratislava, Slovakia, and numerically in Minneapolis, MN, USA, all by single- and multiple-component cosinor and parameter tests. In rats and chickens, these inferential statistical procedures clearly demonstrated a lead in phase of the 24-h cosine curves best fitting all of the duodenal vs. those best fitting all of the pineal melatonin values in each species in 2 geographic (geomagnetic) locations. The 24-h cosine curve of circulating melatonin was found to be in an intermediate phase position. Mechanisms of the phase differences and the contribution of gastrointestinal melatonin to circulating hormone concentrations are discussed.

Indexed as

Chronobiology PhenomenaAnimalsChickensCircadian RhythmData Interpretation, StatisticalDuodenumElectromagnetic FieldsGeographyMaleMelatoninPineal GlandRatsRats, WistarMelatonin

Identifiers

PMID16275498
PMCPMC2662383

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.