ArticleWorld journal of urology2005
Influence of a high-oxalate diet on intestinal oxalate absorption.
Article in World journal of urology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Where does endogenous oxalate come from? - a systematic review of endogenous sources of urinary oxalate.Urolithiasis · 2026Pooled it
- The Relationship between Modern Fad Diets and Kidney Stone Disease: A Systematic Review of Literature.Nutrients · 2021Pooled it
- Influence of a low- and a high-oxalate vegetarian diet on intestinal oxalate absorption and urinary excretion.European journal of clinical nutrition · 2008Trial
- Oxalate Homeostasis in Non-Stone-Forming Chronic Kidney Disease: A Review of Key Findings and Perspectives.Biomedicines · 2023Review
- A case-based review of dietary management of calcium oxalate stones.World journal of urology · 2023Article
- Article
- Methods for the dietary assessment of adult kidney stone formers: a scoping review.Journal of nephrology · 2022Article
- Diet-induced oxalate nephropathy from excessive nut and seed consumption.BMJ case reports · 2020Article
- Oxalate, inflammasome, and progression of kidney disease.Current opinion in nephrology and hypertension · 2016Review
- Nephropathy in dietary hyperoxaluria: A potentially preventable acute or chronic kidney disease.World journal of nephrology · 2014Review
- Enteric hyperoxaluria, recurrent urolithiasis, and systemic oxalosis in patients with Crohn's disease.Pediatric nephrology (Berlin, Germany) · 2012Article
- Variability in urinary oxalate measurements between six international laboratories.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2011Article
- Evidence for net renal tubule oxalate secretion in patients with calcium kidney stones.American journal of physiology. Renal physiology · 2011Article
- Determinants of 24-hour urinary oxalate excretion.Clinical journal of the American Society of Nephrology : CJASN · 2008Article
- Renal lithiasis and nutrition.Nutrition journal · 2006Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperoxaluria is a major risk factor for renal stones. In most cases, it is sustained by increased dietary loads. In healthy individuals with a normal Western diet, the majority of urinary oxalate is usually derived from endogenous metabolism. However, up to 50% may be derived from the diet. We were interested in the effect of a high-oxalate diet on oxalate absorption, not merely on the frequently studied increased oxalate excretion. In study I, 25 healthy volunteers were tested with the [13C2]oxalate absorption test once while following a low-oxalate (63 mg) and once while following a high-oxalate (600 mg) diet for 2 days each. In study II, four volunteers repeated study I, and afterwards continued with a high-oxalate diet (600 mg oxalate/day) for 6 weeks. In the last week, the [13C2]oxalate absorption test was repeated. After 4 weeks of individual normal diet, the oxalate absorption test with a high-oxalate diet was performed again. The results of study I show that the mean [13C2]oxalate absorption under low-oxalate diet was 7.9 +/- 4.0%. In the presence of oxalate-rich food, the percent absorption for the soluble labelled oxalate almost doubled (13.7 +/- 6.3%). The results of study II show that the mean [13C2]oxalate absorption of the four volunteers under low-oxalate diet was 7.3 +/- 1.4%. The absorption increased to 14.7+/-5.2% under 600 mg oxalate. After 6 weeks under a high-oxalate diet, the [13C2]oxalate absorption was significantly decreased (8.2 +/- 1.7%). After the wash-out phase, the absorption was again high (14.1 +/- 2.2%) under the 600 mg oxalate challenge.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.