ArticleCurrent genetics2005
The peculiar distribution of class I and class II aldolases in diatoms and in red algae.
Article in Current genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 21 citations in OpenAlex.
- ASAFind 2.0: multi-class protein targeting prediction for diatoms and algae with complex plastids.The Plant journal : for cell and molecular biology · 2025Article
- Intracellular metabolic pathway distribution in diatoms and tools for genome-enabled experimental diatom research.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Plastid proteome prediction for diatoms and other algae with secondary plastids of the red lineage.The Plant journal : for cell and molecular biology · 2015Article
- Evolution and functional diversification of fructose bisphosphate aldolase genes in photosynthetic marine diatoms.Molecular biology and evolution · 2012Article
- A model for carbohydrate metabolism in the diatom Phaeodactylum tricornutum deduced from comparative whole genome analysis.PloS one · 2008Article
- Protein targeting into complex diatom plastids: functional characterisation of a specific targeting motif.Plant molecular biology · 2007Article
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3 authors at 1 institution in 1 country.
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Abstract
Diatom plastids probably evolved by secondary endocytobiosis from a red alga that was up by a eukaryotic host cell. Apparently, this process increased the complexity of the intracellular distribution of metabolic enzymes. We identified genes encoding fructose-bisphosphate aldolases (FBA) in two centric (Odontella sinensis, Thalassiosira pseudonana) and one pennate (Phaeodactylum tricornutum) diatoms and found that four different aldolases are present in both groups: two plastid targeted class II enzymes (FBAC1 and FBAC2), one cytosolic class II (FBA3) and one cytosolic class I (FBA4) enzyme. The pennate Phaeodactylum possesses an additional plastidic class I enzyme (FBAC5). We verified the classification of the different aldolases in the diatoms by enzymatic characterization of isolated plastids and whole cell extracts. Interestingly, our results imply that in plastids of centric and pennate diatoms mainly either class I or class II aldolases are active. We also identified genes for both class I and class II aldolases in red algal EST databases, thus presenting a fascinating example of the reutilization and recompartmentalization of different aldolase isoenzymes during secondary endocytobiosis but as well demonstrating the limited use of metabolic enzymes as markers for the interpretation of phylogenetic histories in algae.
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