Evidence map›Paper›PMID 16272506›Full record

ArticleJournal of clinical microbiology2005

Use of resequencing oligonucleotide microarrays for identification of Streptococcus pyogenes and associated antibiotic resistance determinants.

Louis Davignon, Elizabeth A Walter, Kate M Mueller, Christopher P Barrozo, David A Stenger, Baochuan Lin

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Resequencing arrays for diagnostics of respiratory pathogens.Methods in molecular biology (Clifton, N.J.) · 2009
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Microarrays in infection and immunity.Current opinion in chemical biology · 2007
    Review
  13. Article
  14. Article
  15. Article
  16. Microarray technology in obstetrics and gynecology: a guide for clinicians.American journal of obstetrics and gynecology · 2006
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Louis DavignonMalcolm Grow Medical Center, Andrews Air Force Base, Maryland 20762, USA.
Elizabeth A Walter
Kate M Mueller
Christopher P Barrozo
David A Stenger
Baochuan Lin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group A streptococci (GAS) are responsible for a wide variety of human infections associated with considerable morbidity and mortality. Ever since the first systematic effort by Lancefield to group Streptococcus species by M protein variants, the detection and characterization of Streptococcus by different methods have been an evolving process. The ideal assay for GAS identification not only would provide quick and accurate diagnostic results but also would reveal antibiotic resistance patterns and genotype information, aiding not only in treatment but in epidemiologic assessment as well. The oligonucleotide microarray is a promising new technology which could potentially address this need. In this study, we evaluated the usefulness of oligonucleotide resequencing microarrays for identifying GAS and its associated antibiotic resistance markers. We demonstrated an assay platform that combines the use of resequencing DNA microarrays with either random nucleic acid amplification or multiplex PCR for GAS detection. When detecting Streptococcus pyogenes from coded clinical samples, this approach demonstrated an excellent concordance with a more established culture method. To this end, we showed the potential of resequencing microarrays for efficient and accurate detection of GAS and its associated antibiotic resistance markers with the benefit of sequencing information from microarray analysis.

Indexed as

Oligonucleotide Array Sequence AnalysisAnti-Bacterial AgentsDrug ResistanceHumansOligonucleotide ProbesStreptococcal InfectionsStreptococcus pyogenesAnti-Bacterial AgentsOligonucleotide Probes

Identifiers

PMID16272506
PMCPMC1287778

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.