ArticleThe Plant cell2005
Transcription and histone modifications in the recombination-free region spanning a rice centromere.
Article in The Plant cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Chromosome painting in plants: history and future perspectives.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026Review
- The deSUMOylase SPF2 and the cohesin regulators SGO2 and CTF18 suppress crossovers near centromeres.Nature plants · 2026Article
- Augmented CENH3 loading is accompanied by transcriptional and epigenetic reprogramming at rice centromeres during meiosis.Genome biology · 2026Article
- Comparison of Recombination Rate, Reference Bias, and Unique Pangenomic Haplotypes inInternational journal of molecular sciences · 2025Article
- Article
- Centromere repositioning and shifts in wheat evolution.Plant communications · 2023Article
- The transcribed centromeric gene OsMRPL15 is essential for pollen development in rice.Plant physiology · 2023Article
- Methylation in the CHH Context Allows to Predict Recombination in Rice.International journal of molecular sciences · 2022Article
- Tempo of Degeneration Across Independently Evolved Nonrecombining Regions.Molecular biology and evolution · 2022Article
- Enriched-GWAS and Transcriptome Analysis to Refine and Characterize a Major QTL for Anaerobic Germination Tolerance in Rice.International journal of molecular sciences · 2021Article
- Epigenetic regulation of centromere function.Cellular and molecular life sciences : CMLS · 2020Review
- The epigenetic regulation of centromeres and telomeres in plants and animals.Comparative cytogenetics · 2020Review
- Transposable elements: genome innovation, chromosome diversity, and centromere conflict.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018Review
- Segmental Duplication of Chromosome 11 and its Implications for Cell Division and Genome-wide Expression in Rice.Scientific reports · 2017Article
- Repression of harmful meiotic recombination in centromeric regions.Seminars in cell & developmental biology · 2016Review
- De Novo Centromere Formation and Centromeric Sequence Expansion in Wheat and its Wide Hybrids.PLoS genetics · 2016Article
- Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3.Molecular biology of the cell · 2016Article
- Gene Expression and Chromatin Modifications Associated with Maize Centromeres.G3 (Bethesda, Md.) · 2015Article
- Expansion of a novel endogenous retrovirus throughout the pericentromeres of modern humans.Genome biology · 2015Article
- Evidence for emergence of sex-determining gene(s) in a centromeric region in Vasconcellea parviflora.Genetics · 2015Article
1 more citing papers are in PubMed but not listed here.
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Centromeres are sites of spindle attachment for chromosome segregation. During meiosis, recombination is absent at centromeres and surrounding regions. To understand the molecular basis for recombination suppression, we have comprehensively annotated the 3.5-Mb region that spans a fully sequenced rice centromere. Although transcriptional analysis showed that the 750-kb CENH3-containing core is relatively deficient in genes, the recombination-free region differs little in gene density from flanking regions that recombine. Likewise, the density of transposable elements is similar between the recombination-free region and flanking regions. We also measured levels of histone H4 acetylation and histone H3 methylation at 176 genes within the 3.5-Mb span. Active genes showed enrichment of H4 acetylation and H3K4 dimethylation as expected, including genes within the core. Our inability to detect sequence or histone modification features that distinguish recombination-free regions from flanking regions that recombine suggest that recombination suppression is an epigenetic feature of centromeres maintained by the assembly of CENH3-containing nucleosomes within the core. CENH3-containing centrochromatin does not appear to be distinguished by a unique combination of H3 and H4 modifications. Rather, the varied distribution of histone modifications might reflect the composition and abundance of sequence elements that inhabit centromeric DNA.
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