Evidence map›Paper›PMID 16272231›Full record

ReviewPostgraduate medical journal2005

Food allergy in children.

V R Baral, J O'B Hourihane

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Postgraduate medical journal, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00461097 (Oral Desensitization to Egg With Subsequent Induction of Tolerance for Egg-Allergic Children), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00461097 phase2completednot on this mapstarted 2007, after this paper: background citation

Oral Desensitization to Egg With Subsequent Induction of Tolerance for Egg-Allergic Children (CoFAR 3)

TypeinterventionalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2007 to 2013Enrolled55ConditionsHypersensitivity, Immediate Hypersensitivity, Food HypersensitivityArmsEgg oral immunotherapy, Control Group
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 66 citations in OpenAlex.

  1. Evaluating an online self-help intervention for parents of children with food allergies.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

V R BaralInfection, Inflammation and Repair Division, University of Southampton, UK.
J O'B Hourihane
University of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy is being increasingly recognised with the highest prevalence being in preschool children. Pathogenesis varies so diagnosis rests on careful history and clinical examination, appropriate use of skin prick and serum-specific IgE testing, food challenge, and supervised elimination diets. A double blind placebo controlled food challenge is the gold standard diagnostic test. Avoidance of the allergenic food is the key towards successful management. IgE mediated food allergy may present as a potentially fatal anaphylactic reaction, and management consists of the appropriate use of adrenaline (epinephrine) and supportive measures. Sensitisation remains a key target for intervention. Disease modifying agents are currently under trial for managing difficult allergies. Management requires a multidisciplinary approach and follow up.

Indexed as

Food HypersensitivityChildDietForecastingHumansImmunoglobulin EReferral and ConsultationSkin TestsT-Lymphocytes, Helper-InducerVaccinationImmunoglobulin E

Identifiers

PMID16272231
PMCPMC1743387
OpenAlexW2159085303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.