ArticleCough (London, England)2005
Cough: are children really different to adults?
Article in Cough (London, England), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 8 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Honey for acute cough in children.The Cochrane database of systematic reviews · 2018Pooled it
- Clinical pathways for chronic cough in children.The Cochrane database of systematic reviews · 2014Pooled it
- Over-the-counter (OTC) medications to reduce cough as an adjunct to antibiotics for acute pneumonia in children and adults.The Cochrane database of systematic reviews · 2014Pooled it
- Inhaled corticosteroids for subacute and chronic cough in adults.The Cochrane database of systematic reviews · 2013Pooled it
- Inhaled corticosteroids for subacute cough in children.The Cochrane database of systematic reviews · 2013Pooled it
- Honey and lozenges for children with non-specific cough.The Cochrane database of systematic reviews · 2009Pooled it
- Anti-histamines for prolonged non-specific cough in children.The Cochrane database of systematic reviews · 2008Pooled it
- Leukotriene receptor antagonist for prolonged non-specific cough in children.The Cochrane database of systematic reviews · 2006Pooled it
- Trial
- Objective Assessment of the Cough: Listening to the Patient's Voice. A Narrative Review.Tuberculosis and respiratory diseases · 2026Article
- Expert opinion and clinical practice recommendations using a modified Delphi approach for pediatric acute cough evaluation and management in India.Lung India : official organ of Indian Chest Society · 2026Article
- Prevalence and Clinical Characteristics of Acute Cough in Indian Pediatric Population: Insights from Real-World Study.Journal of pharmacy & bioallied sciences · 2025Article
- Upper Respiratory Tract Infection-Associated Acute Cough and the Urge to Cough: New Insights for Clinical Practice.Pediatric allergy, immunology, and pulmonology · 2020Review
- The Possible Therapeutic Effects of Some Medicinal Plants for Chronic Cough in Children.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- Wet Cough and Nasal Symptoms in Children: Can We Do Better?Frontiers in pediatrics · 2019Article
- Down-Regulation of Cough during Exercise Is Less Frequent in Healthy Children than Adults. Role of the Development and/or Atopy?Frontiers in physiology · 2017Article
- Maturation of Airway Defensive Reflexes Is Related to Development of Feeding Behavior during Growth in Rabbits.Frontiers in physiology · 2017Article
- Update on Pediatric Cough.Lung · 2016Review
- Impact of Air Pollution on Age and Gender Related Increase in Cough Reflex Sensitivity of Healthy Children in Slovakia.Frontiers in physiology · 2016Article
- What is chronic cough in children?Frontiers in physiology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Worldwide paediatricians advocate that children should be managed differently from adults. In this article, similarities and differences between children and adults related to cough are presented. Physiologically, the cough pathway is closely linked to the control of breathing (the central respiratory pattern generator). As respiratory control and associated reflexes undergo a maturation process, it is expected that the cough would likewise undergo developmental stages as well. Clinically, the 'big three' causes of chronic cough in adults (asthma, post-nasal drip and gastroesophageal reflux) are far less common causes of chronic cough in children. This has been repeatedly shown by different groups in both clinical and epidemiological studies. Therapeutically, some medications used empirically for cough in adults have little role in paediatrics. For example, anti-histamines (in particular H1 antagonists) recommended as a front-line empirical treatment of chronic cough in adults have no effect in paediatric cough. Instead it is associated with adverse reactions and toxicity. Similarly, codeine and its derivatives used widely for cough in adults are not efficacious in children and are contraindicated in young children. Corticosteroids, the other front-line empirical therapy recommended for adults, are also minimally (if at all) efficacious for treating non-specific cough in children. In summary, current data support that management guidelines for paediatric cough should be different to those in adults as the aetiological factors and treatment in children significantly differ to those in adults.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.