Evidence map›Paper›PMID 16269795›Full record

ArticleApplied and environmental microbiology2005

Application of measurements of transepithelial electrical resistance of intestinal epithelial cell monolayers to evaluate probiotic activity.

Trine Danø Klingberg, Maja Herold Pedersen, Avrelija Cencic, Birgitte Bjørn Budde

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Antimicrobial activity ofJournal of animal science and technology · 2025
    Article
  5. Review
  6. Probiotics and the intestinal tight junction barrier function.Frontiers in cell and developmental biology · 2025
    Review
  7. Matrix Metalloproteinase-9 Signaling Regulates Colon Barrier Integrity in Models of HIV Infection.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Coculture Strategy for DevelopingFoods (Basel, Switzerland) · 2021
    Article
  14. Review
  15. Review
  16. International journal of medical sciences · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. NovelFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Trine Danø KlingbergThe Royal Veterinary and Agricultural University, Department of Food Science, Rolighedsvej 30, 4th Floor, DK-1958 Frederiksberg C, Denmark. tdk@kvl.dk
Maja Herold Pedersen
Avrelija Cencic
Birgitte Bjørn Budde

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among five potentially probiotic lactobacilli investigated, Lactobacillus plantarum MF1298 and Lactobacillus salivarius DC5 showed the highest increase in the transepithelial electrical resistance (TER) of polarized monolayers of Caco-2 cells, and this increase was shown to be dose dependent. Furthermore, preincubation with MF1298 attenuated a decrease in TER induced by Listeria monocytogenes.

Indexed as

Caco-2 CellsCell PolarityElectric ImpedanceEpithelial CellsHumansIntestinesLactobacillusListeria monocytogenesProbiotics

Identifiers

PMID16269795
PMCPMC1287686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.