ArticleApplied and environmental microbiology2005
Identifying components of the NF-kappaB pathway in the beneficial Euprymna scolopes-Vibrio fischeri light organ symbiosis.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed.
- Lighting the way: how the squid-Vibrio model can inform thermal impacts on symbiotic dynamics.The Journal of experimental biology · 2026Review
- Review
- Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters.Cell communication and signaling : CCS · 2024Article
- Transcriptomic responses in the nervous system and correlated behavioural changes of a cephalopod exposed to ocean acidification.BMC genomics · 2024Article
- Impact of modeled microgravity stress on innate immunity in a beneficial animal-microbe symbiosis.Scientific reports · 2024Article
- Modeled microgravity alters apoptotic gene expression and caspase activity in the squid-vibrio symbiosis.BMC microbiology · 2022Article
- A peptidoglycan-recognition protein orchestrates the first steps of symbiont recruitment in the squid-vibrio symbiosis.Symbiosis (Philadelphia, Pa.) · 2022Article
- A lasting symbiosis: how the Hawaiian bobtail squid finds and keeps its bioluminescent bacterial partner.Nature reviews. Microbiology · 2021Review
- Roles of Carotenoids in Invertebrate Immunology.Frontiers in immunology · 2019Review
- Peptidoglycan Muropeptides: Release, Perception, and Functions as Signaling Molecules.Frontiers in microbiology · 2019Review
- Characterization of the cell polarity gene crumbs during the early development and maintenance of the squid-vibrio light organ symbiosis.Development genes and evolution · 2017Article
- Comparative immunogenomics of molluscs.Developmental and comparative immunology · 2017Review
- Transcriptome analysis of the white body of the squid Euprymna tasmanica with emphasis on immune and hematopoietic gene discovery.PloS one · 2015Article
- Molecular cloning and mRNA expression of the peptidoglycan recognition protein gene HcPGRP1 and its isoform HcPGRP1a from the freshwater mussel Hyriopsis cumingi.Genetics and molecular biology · 2014Article
- Article
- Eye-specification genes in the bacterial light organ of the bobtail squid Euprymna scolopes, and their expression in response to symbiont cues.Mechanisms of development · 2014Article
- Article
- Innate immune recognition of the microbiota promotes host-microbial symbiosis.Nature immunology · 2013Review
- Immune response-related gene expression profile of a novel molluscan IκB protein member from Manila clam (Ruditapes philippinarum).Molecular biology reports · 2013Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
The Toll/NF-kappaB pathway is a common, evolutionarily conserved innate immune pathway that modulates the responses of animal cells to microbe-associated molecular patterns (MAMPs). Because MAMPs have been implicated as critical elements in the signaling of symbiont-induced development, an expressed sequence tag library from the juvenile light organ of Euprymna scolopes was used to identify members of the Toll/NF-kappaB pathway. Full-length transcripts were identified by using 5' and 3' RACE PCR. Seven transcripts critical for MAMP-induced triggering of the Toll/NF-kappaB phosphorylation cascade have been identified, including receptors, signal transducers, and a transcription factor. Further investigations should elucidate the role of the Toll/NF-kappaB pathway in the initiation of the beneficial symbiosis between E. scolopes and Vibrio fischeri.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.