ArticleEnvironmental health perspectives2005
Proximity to pollution sources and risk of amphibian limb malformation.
Article in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 123 citations in OpenAlex.
- Exposure to common pesticides utilized in northern rice fields of Iran affects survival of non-target species, Pelophylax ridibundus (Amphibia: Ranidae).Environmental science and pollution research international · 2021Article
- Histopathologic and genotoxic effects of deltamethrin on marsh frog, Pelophylax ridibundus (Anura: Ranidae).Environmental science and pollution research international · 2021Article
- Landscape-level toxicant exposure mediates infection impacts on wildlife populations.Biology letters · 2020Article
- Monitoring the morphological integrity of neotropical anurans.Environmental science and pollution research international · 2019Article
- Follow-up ecological studies for cryptic species discoveries: Decrypting the leopard frogs of the eastern U.S.PloS one · 2018Article
- Micronucleus cytome assay in the differential assessment of cytotoxicity and genotoxicity of cadmium and lead inEXCLI journal · 2018Article
- Genetic damage in Rhinella marina populations in habitats affected by agriculture in the middle region of the Sinú River, Colombia.Environmental science and pollution research international · 2017Article
- Habitat quality affects the incidence of morphological abnormalities in the endangered salamander Ambystoma ordinarium.PloS one · 2017Article
- Phalangeal bone anomalies in the European common toad Bufo bufo from polluted environments.Environmental science and pollution research international · 2016Article
- Common toad Rhinella arenarum (Hensel, 1867) and its importance in assessing environmental health: test of micronuclei and nuclear abnormalities in erythrocytes.Environmental monitoring and assessment · 2015Article
- Localized hotspots drive continental geography of abnormal amphibians on U.S. wildlife refuges.PloS one · 2013Article
- Oxidation of retinoic acids in hepatic microsomes of wild bullfrogs Lithobates catesbeianus environmentally-exposed to a gradient of agricultural contamination.Ecotoxicology (London, England) · 2012Article
- Cyanobacteria blooms produce teratogenic retinoic acids.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Morphological abnormalities in frogs from a rice-growing region in NSW, Australia, with investigations into pesticide exposure.Environmental monitoring and assessment · 2011Article
- Road proximity increases risk of skeletal abnormalities in wood frogs from National Wildlife Refuges in Alaska.Environmental health perspectives · 2008Article
- Exploring the role of GIS during community health assessment problem solving: experiences of public health professionals.International journal of health geographics · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The cause of limb deformities in wild amphibian populations remains unclear, even though the apparent increase in prevalence of this condition may have implications for human health. Few studies have simultaneously assessed the effect of multiple exposures on the risk of limb deformities. In a cross-sectional survey of 5,264 hylid and ranid metamorphs in 42 Vermont wetlands, we assessed independent risk factors for nontraumatic limb malformation. The rate of nontraumatic limb malformation varied by location from 0 to 10.2%. Analysis of a subsample did not demonstrate any evidence of infection with the parasite Ribeiroia. We used geographic information system (GIS) land-use/land-cover data to validate field observations of land use in the proximity of study wetlands. In a multiple logistic regression model that included land use as well as developmental stage, genus, and water-quality measures, proximity to agricultural land use was associated with an increased risk of limb malformation (odds ratio = 2.26; 95% confidence interval, 1.42-3.58; p < 0.001). The overall discriminant power of the statistical model was high (C = 0.79). These findings from one of the largest systematic surveys to date provide support for the role of chemical toxicants in the development of amphibian limb malformation and demonstrate the value of an epidemiologic approach to this problem.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.