ArticleEnvironmental health perspectives2005
Personal exposure to ultrafine particles and oxidative DNA damage.
Article in Environmental health perspectives, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 285 citations in OpenAlex.
- Impact of indoor air pollution on DNA damage and chromosome stability: a systematic review.Archives of toxicology · 2024Pooled it
- Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution.Environmental health perspectives · 2010Pooled it
- Inhalation of hydrogenated vegetable oil combustion exhaust and genotoxicity responses in humans.Archives of toxicology · 2021Trial
- No oxidative stress or DNA damage in peripheral blood mononuclear cells after exposure to particles from urban street air in overweight elderly.Mutagenesis · 2015Trial
- Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults.Particle and fibre toxicology · 2015Trial
- An indoor air filtration study in homes of elderly: cardiovascular and respiratory effects of exposure to particulate matter.Environmental health : a global access science source · 2013Trial
- Controlled human wood smoke exposure: oxidative stress, inflammation and microvascular function.Particle and fibre toxicology · 2012Trial
- Towards a validation of the standard and enzyme-linked comet assay: a retrospective variability analysis.Archives of toxicology · 2026Review
- Article
- Hidden danger: The long-term effect of ultrafine particles on mortality and its sociodemographic disparities in New York State.Journal of hazardous materials · 2024Article
- Examining the relationship between land use and childhood leukemia and lymphoma in Tehran.Scientific reports · 2024Article
- Article
- Airborne Exposure of the Cornea to PMInternational journal of molecular sciences · 2023Article
- Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PMIranian journal of basic medical sciences · 2022Article
- Links between chronic exposure to outdoor air pollution and cardiovascular diseases: a review.Environmental chemistry letters · 2022Review
- Exposure to ultrafine particles while walking or bicycling during COVID-19 closures: A repeated measures study in Copenhagen, Denmark.The Science of the total environment · 2021Article
- Association of Prenatal Ambient Air Pollution Exposure With Placental Mitochondrial DNA Copy Number, Telomere Length and Preeclampsia.Frontiers in toxicology · 2021Article
- Exposure to Ultrafine Particles in the Ferroalloy Industry Using a Logbook Method.Nanomaterials (Basel, Switzerland) · 2020Article
- Analysis of the Direct and Indirect Effects of Nanoparticle Exposure on Microglial and Neuronal Cells In Vitro.International journal of molecular sciences · 2020Article
- As the Wind Blows: The Effects of Long-Term Exposure to Air Pollution on Mortality.Journal of the European Economic Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure to ultrafine particles (UFPs) from vehicle exhaust has been related to risk of cardiovascular and pulmonary disease and cancer, even though exposure assessment is difficult. We studied personal exposure in terms of number concentrations of UFPs in the breathing zone, using portable instruments in six 18-hr periods in 15 healthy nonsmoking subjects. Exposure contrasts of outdoor pollution were achieved by bicycling in traffic for 5 days and in the laboratory for 1 day. Oxidative DNA damage was assessed as strand breaks and oxidized purines in mononuclear cells isolated from venous blood the morning after exposure measurement. Cumulated outdoor and cumulated indoor exposures to UFPs each were independent significant predictors of the level of purine oxidation in DNA but not of strand breaks. Ambient air concentrations of particulate matter with an aerodynamic diameter of < or = 10 microm (PM10), nitrous oxide, nitrogen dioxide, carbon monoxide, and/or number concentration of UFPs at urban background or busy street monitoring stations was not a significant predictor of DNA damage, although personal UFP exposure was correlated with urban background concentrations of CO and NO2, particularly during bicycling in traffic. The results indicate that biologic effects of UFPs occur at modest exposure, such as that occurring in traffic, which supports the relationship of UFPs and the adverse health effects of air pollution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.