ArticleMolecular psychiatry2006
Autism spectrum disorders associated with X chromosome markers in French-Canadian males.
Article in Molecular psychiatry, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Male-Dominant Effects of Chd8 Haploinsufficiency on Synaptic Phenotypes during Development in Mouse Prefrontal Cortex.ACS chemical neuroscience · 2024Article
- Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders.Brain communications · 2022Article
- Identification of common genetic risk variants for autism spectrum disorder.Nature genetics · 2019Article
- Genetic risk for schizophrenia and autism, social impairment and developmental pathways to psychosis.Translational psychiatry · 2018Article
- Lack of association between NLGN3, NLGN4, SHANK2 and SHANK3 gene variants and autism spectrum disorder in a Chinese population.PloS one · 2013Article
- Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia.Molecular psychiatry · 2011Article
- X chromosome and suicide.Molecular psychiatry · 2011Article
- Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.Science translational medicine · 2010Article
- Article
- Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism.Genes, brain, and behavior · 2008Article
- Analysis of X chromosome inactivation in autism spectrum disorders.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2008Article
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is now well established that genetic factors play an important role in the pathogenesis of autism disorder and converging lines of evidence suggest the implication of the X chromosome. Using a sample of subjects diagnosed with autism spectrum disorders, exclusively composed of males from French-Canadian (FC) origin, we tested markers covering the entire X chromosome using a family-based association study. Our initial analysis revealed the presence of association at two loci: DXS6789 (P=0.026) and DXS8043 (P=0.0101). In a second step, we added support to the association at DXS8043 using additional markers, additional subjects and a haplotype-based analysis (best obtained P-value=0.00001). These results provide support for the existence of a locus on the X chromosome that predisposes the FC to autism spectrum disorders.
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Registered trials
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