ArticleProceedings of the National Academy of Sciences of the United States of America2005
Three genomes differentially contribute to the biosynthesis of benzoxazinones in hexaploid wheat.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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58 citing papers in PubMed, 134 citations in OpenAlex.
- Integration of the D-Genome Reshapes Gene Transcription, Chromatin Architecture, and Metabolome of Allohexaploid Wheat, Leading to Enhanced Environmental Adaptability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Dual role of benzoxazinoids in plant response to combined drought stress and aphid feeding.Plant biology (Stuttgart, Germany) · 2026Article
- The transcription factor TaMYB31 regulates the benzoxazinoid biosynthetic pathway in wheat.Journal of experimental botany · 2022Article
- Lateral transfers lead to the birth of momilactone biosynthetic gene clusters in grass.The Plant journal : for cell and molecular biology · 2022Article
- Genetic Resources of Cereal Crops for Aphid Resistance.Plants (Basel, Switzerland) · 2022Review
- Horizontal transfer and evolution of the biosynthetic gene cluster for benzoxazinoids in plants.Plant communications · 2022Article
- Pathogen-induced biosynthetic pathways encode defense-related molecules in bread wheat.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Article
- Increased benzoxazinoid (Bx) levels in wheat seedlings via jasmonic acid treatment and etiolation and their effects onBiochemistry and biophysics reports · 2021Article
- The Roots of Rye (International journal of molecular sciences · 2021Article
- Analysis of the chromosomal clustering of Fusarium-responsive wheat genes uncovers new players in the defence against head blight disease.Scientific reports · 2021Article
- Transcriptome Analysis Reveals a Potential Role of Benzoxazinoid in Regulating Stem Elongation in the Wheat MutantFrontiers in genetics · 2021Article
- The Effectiveness of Physical and Chemical Defense Responses of Wild Emmer Wheat Against Aphids Depends on Leaf Position and Genotype.Frontiers in plant science · 2021Article
- Comparative functional genomics analysis of cytochrome P450 gene superfamily in wheat and maize.BMC plant biology · 2020Article
- TaCYP81D5, one member in a wheat cytochrome P450 gene cluster, confers salinity tolerance via reactive oxygen species scavenging.Plant biotechnology journal · 2020Article
- Comparative transcriptomic and metabolic analysis of wild and domesticated wheat genotypes reveals differences in chemical and physical defense responses against aphids.BMC plant biology · 2020Article
- Transcriptome Dynamics of the Inflorescence in Reciprocally Formed AllopolyploidFrontiers in genetics · 2020Article
- Molecular Characterization of Auxin Efflux Carrier- ABCB1 in hexaploid wheat.Scientific reports · 2019Article
- Deletion of the benzoxazinoid detoxification gene NAT1 in Fusarium graminearum reduces deoxynivalenol in spring wheat.PloS one · 2019Article
- Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hexaploid wheat (Triticum aestivum) accumulates benzoxazinones (Bxs) as defensive compounds. Previously, we found that five Bx biosynthetic genes, TaBx1-TaBx5, are located on each of the three genomes (A, B, and D) of hexaploid wheat. In this study, we isolated three homoeologous cDNAs of each TaBx gene to estimate the contribution of individual homoeologous TaBx genes to the biosynthesis of Bxs in hexaploid wheat. We analyzed their transcript levels by homoeolog- or genome-specific quantitative RT-PCR and the catalytic properties of their translation products by kinetic analyses using recombinant TaBX enzymes. The three homoeologs were transcribed differentially, and the ratio of the individual homoeologous transcripts to total homoeologous transcripts also varied with the tissue, i.e., shoots or roots, as well as with the developmental stage. Moreover, the translation products of the three homoeologs had different catalytic properties. Some TaBx homoeologs were efficiently transcribed, but the translation products showed only weak enzymatic activities, which inferred their weak contribution to Bx biosynthesis. Considering the transcript levels and the catalytic properties collectively, we concluded that the homoeologs on the B genome generally contributed the most to the Bx biosynthesis in hexaploid wheat, especially in shoots. In tetraploid wheat and the three diploid progenitors of hexaploid wheat, the respective transcript levels of the TaBx homoeologs were similar in ratio to those observed in hexaploid wheat. This result indicates that the genomic bias in the transcription of the TaBx genes in hexaploid wheat originated in the diploid progenitors and has been retained through the polyploidization.
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