Evidence map›Paper›PMID 16258796›Full record

SynthesisZeitschrift fur Kardiologie2005

[Role of hormone-replacement therapy for prevention of coronary artery disease in women].

C Gohlke-Bärwolf, C von Schacky

Abstract readEnglish AbstractMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Zeitschrift fur Kardiologie, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

C Gohlke-BärwolfKlinische Kardiologie I, Herzzentrum Bad Krozingen, Südring 15, 79189 Bad Krozingen, Germany. christa.gohlke-baerwolf@herzzentrum.de
C von Schacky

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The postmenopausal increase in the incidence of coronary artery disease implied a protective effect of estrogens. Nonrandomized, clinical and experimental studies have supported this notion. In the first randomized study (HERS 1998) no protective effect on prognosis of postmenopausal women with coronary artery disease was demonstrated. Also, in healthy postmenopausal women no beneficial effect of a hormone-replacement therapy on coronary events was shown (WHI-Study 2002, 2004). Therefore, hormone-replacement therapy is not recommended for prophylaxis of cardiovascular disease in healthy women or in women with documented coronary artery disease (Recommendation class I, evidence-level A). The continuation or the start of a hormone- replacement therapy is only justified for therapy of severe menopausal symptoms. Women should be informed that changes in lifestyle including not smoking, a heart healthy diet, and regular exercise are the most important measures to prevent cardiovascular diseases.

Indexed as

Clinical Trials as TopicCoronary DiseaseEstrogen Replacement TherapyEstrogensEvidence-Based MedicineFemaleHumansIncidencePractice Guidelines as TopicPractice Patterns, Physicians'Preventive MedicineRisk AssessmentRisk FactorsTreatment OutcomeWomen's HealthEstrogens

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.