ReviewThe Journal of molecular diagnostics : JMD2005
Molecular diagnosis of severe acute respiratory syndrome: the state of the art.
Review in The Journal of molecular diagnostics : JMD, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Diagnostic Techniques for COVID-19: A Mini-review of Early Diagnostic Methods.Journal of analysis and testing · 2021Review
- Laboratory diagnosis of novel corona virus (2019-nCoV)-present and the future.The Indian journal of tuberculosis · 2020Review
- Laboratory diagnosis of emerging human coronavirus infections - the state of the art.Emerging microbes & infections · 2020Review
- Coronavirus Detection in the Clinical Microbiology Laboratory: Are We Ready for Identifying and Diagnosing a Novel Virus?Clinics in laboratory medicine · 2020Review
- The diagnosis of SARS-CoV2 pneumonia: A review of laboratory and radiological testing results.Journal of medical virology · 2020Review
- The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents.Molecules (Basel, Switzerland) · 2020Review
- Layer-By-Layer Nanocoating of Antiviral Polysaccharides on Surfaces to Prevent Coronavirus Infections.Molecules (Basel, Switzerland) · 2020Review
- Pathogenic viruses: Molecular detection and characterization.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020Review
- The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Review
- Evidence and possible mechanisms of rare maternal-fetal transmission of SARS-CoV-2.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2020Review
- The scanning electron microscope in microbiology and diagnosis of infectious disease.Scientific reports · 2016Article
- Viral glycoproteins: biological role and application in diagnosis.Virusdisease · 2016Review
- Differential expression of serum/plasma proteins in various infectious diseases: specific or nonspecific signatures.Proteomics. Clinical applications · 2014Review
- Development of an enzyme-linked immunosorbent assay-based test with a cocktail of nucleocapsid and spike proteins for detection of severe acute respiratory syndrome-associated coronavirus-specific antibody.Clinical and vaccine immunology : CVI · 2009Article
- Emerging pathogens: challenges and successes of molecular diagnostics.The Journal of molecular diagnostics : JMD · 2008Review
- Evolution of genomes, host shifts and the geographic spread of SARS-CoV and related coronaviruses.Cladistics : the international journal of the Willi Hennig Society · 2008Article
- Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).Perspectives in medical virology · 2006Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Severe acute respiratory syndrome (SARS) first appeared in Guangdong Province, China, in November 2002. Although virus isolation and serology were useful early in the SARS outbreak for diagnosing new cases, these tests are not generally useful because virus culture requires a BSL-3 laboratory and seroconversion is often delayed until 2 to 3 weeks after infection. The first qualitative reverse transcriptase-polymerase chain reaction tests for SARS-coronavirus (CoV) were sensitive and capable of detecting 1 to 10 genome equivalents. These assays were quickly supplemented with quantitative real-time assays that helped elucidate the natural history of SARS, particularly the initial presence of low viral loads in the upper respiratory tract and high viral loads in the lower respiratory tract. The unique natural history of SARS-CoV infection dictates the testing of both respiratory and nonrespiratory specimens, the testing of multiple specimens from the same patient, and sending out positives to be confirmed by a reference laboratory. Commercially available reverse transcriptase-polymerase chain reaction tests for SARS have recently appeared; however, meaningful evaluations of these assays have not yet been performed and their true performance has not been determined. These and other issues related to diagnosis of SARS-CoV infection are discussed in this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.