Evidence map›Paper›PMID 16257939›Full record

ArticleAmerican journal of public health2005

Racializing drug design: implications of pharmacogenomics for health disparities.

Sandra Soo-Jin Lee

Abstract read
In one paragraph

Article in American journal of public health, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience.Genetics in medicine : official journal of the American College of Medical Genetics · 2008
    Trial
  2. Article
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  4. Article
  5. Use of Race in Kidney Research and Medicine: Concepts, Principles, and Practice.Clinical journal of the American Society of Nephrology : CJASN · 2022
    Article
  6. Health equality, race and pharmacogenomics.British journal of clinical pharmacology · 2022
    Review
  7. Article
  8. Article
  9. Genetic Ancestry Analysis Reveals Misclassification of Commonly Used Cancer Cell Lines.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
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  11. Article
  12. Article
  13. Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sandra Soo-Jin LeeStanford Center for Biomedical Ethics, Stanford University, Palo Alto, CA 94304, USA. sandra.lee@stanford.edu

Funding

NHLBI NIH HHS K01 HL72465
6 · The paper itself

Abstract

Current practices of using "race" in pharmacogenomics research demands consideration of the ethical and social implications for understandings of group difference and for efforts to eliminate health disparities. This discussion focuses on an "infrastructure of racialization" created by current trajectories of research on genetic differences among racially identified groups, the use of race as a proxy for risk in clinical practice, and increasing interest in new market niches by the pharmaceutical industry. The confluence of these factors has resulted in the conflation of genes, disease, and race. I argue that public investment in pharmacogenomics requires careful consideration of current inequities in health status and social and ethical concerns over reifying race and issues of distributive justice.

Indexed as

Drug DesignHealth Services AccessibilityRacial GroupsHealth PolicyHumansPharmacogeneticsUnited StatesBiomedical and Behavioral ResearchGenetics and ReproductionHealth Care and Public Health

Identifiers

PMID16257939
PMCPMC1449497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.