Evidence map›Paper›PMID 16256006›Full record

ReviewCurrent atherosclerosis reports2005

Gender differences in lipoprotein metabolism and dietary response: basis in hormonal differences and implications for cardiovascular disease.

Robert H Knopp, Pathmaja Paramsothy, Barbara M Retzlaff, Brian Fish, Carolyn Walden, Alice Dowdy, Christine Tsunehara, Keiko Aikawa, Marian C Cheung

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 148 citations in OpenAlex.

  1. Pooled it
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  15. Sex-Specific Differences in Kidney Function and Blood Pressure Regulation.International journal of molecular sciences · 2024
    Review
  16. Article
  17. Determinants of obesity in Latin America.Nature metabolism · 2024 · on this map
    Review
  18. Article
  19. Article
  20. Gene-Nutrient Interactions in Obesity:International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Robert H KnoppNorthwest Lipid Research Clinic, University of Washington, Box 359720, Seattle, WA 98104, USA. rhknopp@u.washington.edu
Pathmaja Paramsothy
Barbara M Retzlaff
Brian Fish
Carolyn Walden
Alice Dowdy
Christine Tsunehara
Keiko Aikawa
Marian C Cheung
University of Washington · US

Funding

PILOT STUDY--CLINICAL NUTRITION RESEARCHP30DK035816 · NIDDK · UNIVERSITY OF WASHINGTON · PI Ellen A Schur · 1986 to 2026
$30.4M
NIDDK NIH HHS DK-35816
6 · The paper itself

Abstract

The transport of fat in the blood stream is approximately twice as fast in women as men. Disease states such as obesity and diabetes are associated with greater lipoprotein abnormalities in women compared with men. A greater increment in cardiovascular disease risk in women is linked to these abnormalities. A greater change in triglyceride level and a lesser change in low-density lipoprotein are observed in women than men with high-carbohydrate or high-fat feeding. Most consistent are greater changes in high-density lipoprotein (HDL), HDL2, and apolipoprotein A-I levels in women compared with men with high-carbohydrate or high-fat feeding. Dietary fat restriction in women appears to have a less beneficial lipoprotein effect than in men. Dietary fat restriction for heart disease prevention may be less ideal in women than in men.

Indexed as

AndrogensCardiovascular DiseasesCholesterol, HDLCholesterol, LDLDietEstrogensFemaleHumansLipid MetabolismLipoproteinsMaleRisk AssessmentSensitivity and SpecificitySex FactorsAndrogensCholesterol, HDLCholesterol, LDLEstrogensLipoproteins

Identifiers

PMID16256006
OpenAlexW2052926891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.