Evidence map›Paper›PMID 16256003›Full record

ReviewCurrent atherosclerosis reports2005

Influence of dietary carbohydrate and fat on LDL and HDL particle distributions.

Patty W Siri, Ronald M Krauss

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Current atherosclerosis reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 97 citations in OpenAlex.

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  15. Frontiers in nutrition · 2021
    Article
  16. Article
  17. Review
  18. Nutrients · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Patty W SiriDepartment of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA.
Ronald M Krauss
Institute for Atherosclerosis Research · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Variations in the size and density distributions of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles have been related to risk for cardiovascular disease. In particular, increased levels of small, dense LDL particles, together with reduced levels of large HDL and increases in small HDL, are integral features of the atherogenic dyslipidemia found in patients with insulin resistance, obesity, and metabolic syndrome. Increased dietary carbohydrates, particularly simple sugars and starches with high glycemic index, can increase levels of small, dense LDL and HDL, primarily by mechanisms that involve increasing plasma triglyceride concentrations. Low-carbohydrate diets may have the opposite effects. Diets with differing fatty acid composition can also influence LDL and HDL particle distributions.

Indexed as

Cholesterol, HDLCholesterol, LDLDietary CarbohydratesDietary FatsFemaleHumansHyperlipidemiasMaleParticle SizeRisk AssessmentSensitivity and SpecificityCholesterol, HDLCholesterol, LDLDietary CarbohydratesDietary Fats

Identifiers

PMID16256003
OpenAlexW2007604827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.