ArticleJournal of virology2005
Actin cytoskeleton is involved in targeting of a viral Hsp70 homolog to the cell periphery.
Article in Journal of virology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Elucidating the Subcellular Localization of GLRaV-3 Proteins Encoded by the Unique Gene Block inBiomolecules · 2024Article
- Plasmodesmata-Involved Battle Against Pathogens and Potential Strategies for Strengthening Hosts.Frontiers in plant science · 2021Review
- BCL2-ASSOCIATED ATHANOGENE4 Regulates the KAT1 Potassium Channel and Controls Stomatal Movement.Plant physiology · 2019Article
- Plasma membrane-associated cation-binding protein 1-like protein negatively regulates intercellular movement of BaMV.Journal of experimental botany · 2017Article
- A novel block of plant virus movement genes.Molecular plant pathology · 2017Article
- Identification of Ourmiavirus 30K movement protein amino acid residues involved in symptomatology, viral movement, subcellular localization and tubule formation.Molecular plant pathology · 2016Article
- The ER-Membrane Transport System Is Critical for Intercellular Trafficking of the NSm Movement Protein and Tomato Spotted Wilt Tospovirus.PLoS pathogens · 2016Article
- Soybean actin-depolymerizing factor 2 interacts with Soybean mosaic virus-encoded P3 protein.Virus genes · 2015Article
- The cell biology of Tobacco mosaic virus replication and movement.Frontiers in plant science · 2013Article
- 6K2-induced vesicles can move cell to cell during turnip mosaic virus infection.Frontiers in microbiology · 2013Article
- Contribution of host intracellular transport machineries to intercellular movement of turnip mosaic virus.PLoS pathogens · 2013Article
- Viral and cellular factors involved in Phloem transport of plant viruses.Frontiers in plant science · 2013Article
- The closterovirus-derived gene expression and RNA interference vectors as tools for research and plant biotechnology.Frontiers in microbiology · 2013Article
- Tubule-guided cell-to-cell movement of a plant virus requires class XI myosin motors.PLoS pathogens · 2011Article
- To gate, or not to gate: regulatory mechanisms for intercellular protein transport and virus movement in plants.Molecular plant · 2011Review
- Review
- Cellular pathways for viral transport through plasmodesmata.Protoplasma · 2011Review
- Inhibitors of myosin, but not actin, alter transport through Tradescantia plasmodesmata.Protoplasma · 2011Article
- Biology of callose (β-1,3-glucan) turnover at plasmodesmata.Protoplasma · 2011Review
- Cucumber mosaic virus movement protein severs actin filaments to increase the plasmodesmal size exclusion limit in tobacco.The Plant cell · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The cell-to-cell movement of plant viruses involves translocation of virus particles or nucleoproteins to and through the plasmodesmata (PDs). As we have shown previously, the movement of the Beet yellows virus requires the concerted action of five viral proteins including a homolog of cellular approximately 70-kDa heat shock proteins (Hsp70h). Hsp70h is an integral component of the virus particles and is also found in PDs of the infected cells. Here we investigate subcellular distribution of Hsp70h using transient expression of Hsp70h fused to three spectrally distinct fluorescent proteins. We found that fluorophore-tagged Hsp70h forms motile granules that are associated with actin microfilaments, but not with microtubules. In addition, immobile granules were observed at the cell periphery. A pairwise appearance of these granules at the opposite sides of cell walls and their colocalization with the movement protein of Tobacco mosaic virus indicated an association of Hsp70h with PDs. Treatment with various cytoskeleton-specific drugs revealed that the intact actomyosin motility system is required for trafficking of Hsp70h in cytosol and its targeting to PDs. In contrast, none of the drugs interfered with the PD localization of Tobacco mosaic virus movement protein. Collectively, these findings suggest that Hsp70h is translocated and anchored to PDs in association with the actin cytoskeleton.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.