ArticleRNA (New York, N.Y.)2005
MAASE: an alternative splicing database designed for supporting splicing microarray applications.
Article in RNA (New York, N.Y.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- Plant ISOform sequencing database (PISO): a comprehensive repertory of full-length transcripts in plants.Plant biotechnology journal · 2019Article
- Review: Alternative Splicing (AS) of Genes As An Approach for Generating Protein Complexity.Current genomics · 2013Article
- Alternative splicing for diseases, cancers, drugs, and databases.TheScientificWorldJournal · 2013Review
- Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites.Nucleic acids research · 2012Article
- A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis.PloS one · 2009Article
- Article
- A procedure for identifying homologous alternative splicing events.BMC bioinformatics · 2007Article
- A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.Genes & development · 2007Article
- SpliceMiner: a high-throughput database implementation of the NCBI Evidence Viewer for microarray splice variant analysis.BMC bioinformatics · 2007Article
- Profiling alternatively spliced mRNA isoforms for prostate cancer classification.BMC bioinformatics · 2006Article
- Characteristics and regulatory elements defining constitutive splicing and different modes of alternative splicing in human and mouse.RNA (New York, N.Y.) · 2005Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Alternative splicing is a prominent feature of higher eukaryotes. Understanding of the function of mRNA isoforms and the regulation of alternative splicing is a major challenge in the post-genomic era. The development of mRNA isoform sensitive microarrays, which requires precise splice-junction sequence information, is a promising approach. Despite the availability of a large number of mRNAs and ESTs in various databases and the efforts made to align transcript sequences to genomic sequences, existing alternative splicing databases do not offer adequate information in an appropriate format to aid in splicing array design. Here we describe our effort in constructing the Manually Annotated Alternatively Spliced Events (MAASE) database system, which is specifically designed to support splicing microarray applications. MAASE comprises two components: (1) a manual/computational annotation tool for the efficient extraction of critical sequence and functional information for alternative splicing events and (2) a user-friendly database of annotated events that allows convenient export of information to aid in microarray design and data analysis. We provide a detailed introduction and a step-by-step user guide to the MAASE database system to facilitate future large-scale annotation efforts, integration with other alternative splicing databases, and splicing array fabrication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.