Evidence map›Paper›PMID 16251336›Full record

ArticleAntimicrobial agents and chemotherapy2005

Multiplex PCR for simultaneous detection of macrolide and tetracycline resistance determinants in streptococci.

Surbhi Malhotra-Kumar, Christine Lammens, Jasper Piessens, Herman Goossens

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Article
  2. Sudden re-emergence ofNew microbes and new infections · 2026
    Article
  3. Early-life carriage and antibiotic resistance ofFrontiers in microbiology · 2026
    Article
  4. Efflux-Mediated Macrolide Resistance in ClinicalAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Molecular Characterization ofMicroorganisms · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Antibiotic Resistance and Serotypes Distribution inPolish journal of microbiology · 2024
    Article
  10. Article
  11. Article
  12. Microbiological and Molecular Investigation of Antimicrobial Resistance inAnimals : an open access journal from MDPI · 2024
    Article
  13. Article
  14. Occurrence of Antimicrobial-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  15. Veterinary sciences · 2024
    Article
  16. Article
  17. Article
  18. Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Surbhi Malhotra-KumarBelgian Reference Center for Group A Streptococcus, University of Antwerp, Belgium. surbhi.malhotra@ua.ac.be
Christine Lammens
Jasper Piessens
Herman Goossens

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [erm(A), erm(B), and mef(A/E)] and tetracyclines [tet(M), tet(O), tet(K), and tet(L)] in streptococci.

Indexed as

Drug Resistance, BacterialMacrolidesPolymerase Chain ReactionStreptococcusTetracycline ResistanceMacrolides

Identifiers

PMID16251336
PMCPMC1280148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.