Evidence map›Paper›PMID 16251327›Full record

ArticleAntimicrobial agents and chemotherapy2005

Recombination between the dfrA12-orfF-aadA2 cassette array and an aadA1 gene cassette creates a hybrid cassette, aadA8b.

Alicia M Gestal, H W Stokes, Sally R Partridge, Ruth M Hall

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Diverse Gene Cassette Arrays Prevail in CommensalFrontiers in microbiology · 2020
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. First Report of bla(IMP-8) in Raoultella planticola.Antimicrobial agents and chemotherapy · 2014
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alicia M GestalDepartment of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia.
H W Stokes
Sally R Partridge
Ruth M Hall

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homologous recombination between closely related gene cassettes, such as aadA1 and aadA2, which are 89% identical, can create hybrid cassettes and hybrids of existing cassette arrays. A new cassette array, dfrA12-orfF-aadA8b, which was created by such a recombination event occurring within the aadA2 cassette in the dfrA12-orfF-aadA2 array, has been identified.

Indexed as

Recombination, GeneticBase SequenceEndoribonucleasesEscherichia coli ProteinsMolecular Sequence DataNucleotidyltransferasesEndoribonucleasesEscherichia coli Proteinsgentamicin 2''-nucleotidyltransferaseNucleotidyltransferasesrng protein, E coli

Identifiers

PMID16251327
PMCPMC1280176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.