ArticlePlant molecular biology2005
Structural, functional, and phylogenetic characterization of a large CBF gene family in barley.
Article in Plant molecular biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers.
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Who cites it
126 citing papers in PubMed, 276 citations in OpenAlex.
- Identification of adaptive selection footprints and adaptation strategies of hulless barley (Hordeum vulgare var. coeleste) on the Qinghai-Tibet Plateau.BMC genomics · 2026Article
- Temporal regulation of gene expression during auxin-triggered crown root formation in barley: an integrated approach.Plant & cell physiology · 2025Article
- Genome-wide analysis of the CBF gene family and their transcriptional response to cold stress in Hibiscus mutabilis.Scientific reports · 2025Article
- Genome-wide analysis of C-repeat binding factor (CBF) family members in Pennisetum glaucum and the function of PgCBF21 under cold stress.BMC plant biology · 2025Article
- Feedback transcription regulation between OsNAC3 and OsDREB1A promotes postgermination growth in rice.Science advances · 2025Article
- Identification of Cold Tolerance Transcriptional Regulatory Genes in Seedlings ofInternational journal of molecular sciences · 2024Article
- Low frequency of the wild-type freezing-tolerance LsCBF7 allele among lettuce population suggests a negative selection during domestication and breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Advances and opportunities in unraveling cold-tolerance mechanisms in the world's primary staple food crops.The plant genome · 2024Review
- Current status for utilization of cold resistance genes and strategies in wheat breeding program.Frontiers in genetics · 2024Review
- Genome-Wide Identification of the CBF Gene Family and ICE Transcription Factors in Walnuts and Expression Profiles under Cold Conditions.International journal of molecular sciences · 2023Article
- TheCells · 2023Review
- Genetic Mechanisms of Cold Signaling in Wheat (Life (Basel, Switzerland) · 2022Review
- Cellular Protein Trafficking: A New Player in Low-Temperature Response Pathway.Plants (Basel, Switzerland) · 2022Review
- Phylotranscriptomics Resolves the Phylogeny of Pooideae and Uncovers Factors for Their Adaptive Evolution.Molecular biology and evolution · 2022Article
- ICE-CBF-COR Signaling Cascade and Its Regulation in Plants Responding to Cold Stress.International journal of molecular sciences · 2022Review
- Genome-Wide Survey Indicates Diverse Physiological Roles ofInternational journal of molecular sciences · 2022Article
- Overexpression ofPeerJ · 2022Article
- The Breeding of Winter-Hardy Malting Barley.Plants (Basel, Switzerland) · 2021Review
- Genome-wide identification and expression profiling of DREB genes in Saccharum spontaneum.BMC genomics · 2021Article
- Identification of the Genetic Basis of Response to De-Acclimation in Winter Barley.International journal of molecular sciences · 2021Article
66 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CBFs are key regulators in the Arabidopsis cold signaling pathway. We used Hordeum vulgare (barley), an important crop and a diploid Triticeae model, to characterize the CBF family from a low temperature tolerant cereal. We report that barley contains a large CBF family consisting of at least 20 genes (HvCBFs) comprising three multigene phylogenetic groupings designated the HvCBF1-, HvCBF3-, and HvCBF4-subgroups. For the HvCBF1- and HvCBF3-subgroups, there are comparable levels of phylogenetic diversity among rice, a cold-sensitive cereal, and the cold-hardy Triticeae. For the HvCBF4-subgroup, while similar diversity levels are observed in the Triticeae, only a single ancestral rice member was identified. The barley CBFs share many functional characteristics with dicot CBFs, including a general primary domain structure, transcript accumulation in response to cold, specific binding to the CRT motif, and the capacity to induce cor gene expression when ectopically expressed in Arabidopsis. Individual HvCBF genes differed in response to abiotic stress types and in the response time frame, suggesting different sets of HvCBF genes are employed relative to particular stresses. HvCBFs specifically bound monocot and dicot cor gene CRT elements in vitro under both warm and cold conditions; however, binding of HvCBF4-subgroup members was cold dependent. The temperature-independent HvCBFs activated cor gene expression at warm temperatures in transgenic Arabidopsis, while the cold-dependent HvCBF4-subgroup members of three Triticeae species did not. These results suggest that in the Triticeae - as in Arabidopsis - members of the CBF gene family function as fundamental components of the winter hardiness regulon.
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