ArticlePlant physiology2005
Genetic and molecular analyses of natural variation indicate CBF2 as a candidate gene for underlying a freezing tolerance quantitative trait locus in Arabidopsis.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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73 citing papers in PubMed, 167 citations in OpenAlex.
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- Transcriptome-Based Identification of Novel Transcription Factors Regulating Seed Storage Proteins in Rice.Plants (Basel, Switzerland) · 2025Article
- Parallel evolution of salinity tolerance inScience advances · 2025Article
- Genetic Foundation of Leaf Senescence: Insights from Natural and Cultivated Plant Diversity.Plants (Basel, Switzerland) · 2024Review
- A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Molecular mapping of two novel cold resistance genes in common wheat by 660K SNP array.Molecular breeding : new strategies in plant improvement · 2023Article
- FER and LecRK show haplotype-dependent cold-responsiveness and mediate freezing tolerance in Lotus japonicus.Plant physiology · 2023Article
- Flower transcriptional response to long term hot and cold environments inFrontiers in plant science · 2023Article
- Isolation and Functional Analysis ofInternational journal of molecular sciences · 2022Article
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- Genetics as a key to improving crop photosynthesis.Journal of experimental botany · 2022Article
- Distinct Cold Acclimation of Productivity Traits inInternational journal of molecular sciences · 2022Review
- A QTL approach in faba bean highlights the conservation of genetic control of frost tolerance among legume species.Frontiers in plant science · 2022Article
- A De Novo Transcriptome Analysis Identifies Cold-Responsive Genes in the Seeds ofBioMed research international · 2022Article
- The Photoperiod: Handling and Causing Stress in Plants.Frontiers in plant science · 2021Review
- Genome-wide association study identifies favorable SNP alleles and candidate genes for frost tolerance in pea.BMC genomics · 2020Article
- Natural variation of photosynthetic efficiency in Arabidopsis thaliana accessions under low temperature conditions.Plant, cell & environment · 2020Article
- The cold response regulator CBF1 promotes Arabidopsis hypocotyl growth at ambient temperatures.The EMBO journal · 2020Article
- Genetic and physiological mechanisms of freezing tolerance in locally adapted populations of a winter annual.American journal of botany · 2020Article
- Quantitative Trait Loci for Freezing Tolerance in a Lowland x Upland Switchgrass Population.Frontiers in plant science · 2019Article
13 more citing papers are in PubMed but not listed here.
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6 authors at 3 institutions in 1 country.
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Abstract
Natural variation for freezing tolerance is a major component of adaptation and geographic distribution of plant species. However, little is known about the genes and molecular mechanisms that determine its naturally occurring diversity. We have analyzed the intraspecific freezing tolerance variation existent between two geographically distant accessions of Arabidopsis (Arabidopsis thaliana), Cape Verde Islands (Cvi) and Landsberg erecta (Ler). They differed in their freezing tolerance before and after cold acclimation, as well as in the cold acclimation response in relation to photoperiod conditions. Using a quantitative genetic approach, we found that freezing tolerance differences after cold acclimation were determined by seven quantitative trait loci (QTL), named FREEZING TOLERANCE QTL 1 (FTQ1) to FTQ7. FTQ4 was the QTL with the largest effect detected in two photoperiod conditions, while five other FTQ loci behaved as photoperiod dependent. FTQ4 colocated with the tandem repeated genes C-REPEAT BINDING FACTOR 1 (CBF1), CBF2, and CBF3, which encode transcriptional activators involved in the cold acclimation response. The low freezing tolerance of FTQ4-Cvi alleles was associated with a deletion of the promoter region of Cvi CBF2, and with low RNA expression of CBF2 and of several CBF target genes. Genetic complementation of FTQ4-Cvi plants with a CBF2-Ler transgene suggests that such CBF2 allelic variation is the cause of CBF2 misexpression and the molecular basis of FTQ4.
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