Evidence map›Paper›PMID 16243778›Full record

ArticleArchaea (Vancouver, B.C.)2005

Role of the precorrin 6-X reductase gene in cobamide biosynthesis in Methanococcus maripaludis.

Wonduck Kim, Tiffany A Major, William B Whitman

Open access · hybridAbstract read
In one paragraph

Article in Archaea (Vancouver, B.C.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Skin-associatedmSphere · 2025
    Article
  2. Skin-associatedbioRxiv : the preprint server for biology · 2024
    Article
  3. Article
  4. Journal of bacteriology · 2021
    Article
  5. Genomic and proteomic characterization of "Candidatus Nitrosopelagicus brevis": an ammonia-oxidizing archaeon from the open ocean.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Wonduck KimDepartment of Microbiology, The Ohio State University, Columbus, OH, USA.
Tiffany A Major
William B Whitman
University of Georgia · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Methanococcus maripaludis strain JJ, deletion of the homolog to cbiJ, which encodes the corrin biosynthetic enzyme precorrin 6-X reductase, yielded an auxotroph that required either cobamide or acetate for good growth. This phenotype closely resembled that of JJ117, a mutant in which tandem repeats were introduced into the region immediately downstream of the homolog of cbiJ. Mutant JJ117 also produced low quantities of cobamides, about 15 nmol g(-1) protein or 1-2% of the amount found in wild-type cells. These results confirm the role of the cbiJ homolog in cobamide biosynthesis in the Archaea and suggest the presence of low amounts of a bypass activity in these organisms.

Indexed as

Base SequenceCobamidesGenes, ArchaealMethanococcusMolecular Sequence DataOxidoreductasesCobamidesOxidoreductasesprecorrin 6x oxidoreductase

Identifiers

PMID16243778
PMCPMC2685584
OpenAlexW2107690392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.