Evidence map›Paper›PMID 16240061›Full record

Trial reportWorld journal of surgery2005

Prospective randomized trial comparing Billroth I and Roux-en-Y procedures after distal gastrectomy for gastric carcinoma.

Makoto Ishikawa, Joji Kitayama, Shoichi Kaizaki, Hiroshi Nakayama, Hironori Ishigami, Shin Fujii, Hiroyuki Suzuki, Tomomi Inoue, Akihiro Sako, Masahiro Asakage and 3 more

3 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in World journal of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 53 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 6 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01142271 phase3unknown statusnot on this mapstarted 2010, after this paper: background citation

Comparison of Billroth-I and Roux-en-Y Reconstruction After Distal Subtotal Gastrectomy for Gastric Cancer Patients : Prospective Randomized Study

TypeinterventionalSponsorAjou University School of MedicineRan2010 to 2012Enrolled120ConditionsGastrectomyArmsBillroth-I, Roux en Y
NCT01257711 nacompletednot on this mapstarted 2008, after this paper: background citation

A Prospective Randomised Study Comparing Billroth II With Roux-en-Y Reconstruction After Radical Distal Subtotal Gastrectomy for Gastric Cancer

TypeinterventionalSponsorNational Healthcare Group, SingaporeRan2008 to 2020Enrolled96ConditionsGastric Cancer, Stomach Cancer, GastrectomyArmsRoux-en-Y or Billroth II
NCT02054637 phase2unknown statusnot on this mapstarted 2014, after this paper: background citation

Resolving Bile Reflux by Lanreotide in Patients With Roux-en-Y Gastrojejunostomy

TypeinterventionalSponsorUniversitair Ziekenhuis BrusselRan2014 to 2016Enrolled10ConditionsAcid Reflux Esophagitis, Non-acid Reflux EsophagitisArmsLanreotide
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 6 syntheses or guidelines pooled it, 113 citations in OpenAlex.

  1. Guideline
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  8. A comparison of postoperative quality of life and dysfunction after Billroth I and Roux-en-Y reconstruction following distal gastrectomy for gastric cancer: results from a multi-institutional RCT.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2012
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  19. Comparison of the Long-term Outcome Between Billroth-I and Roux-en-Y Reconstruction Following Distal Gastrectomy for Gastric Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Makoto IshikawaDepartment of Surgery, Division of Surgical Oncology, The University of Tokyo, 7-3-1 Hongo, Bankyo-ku, Tokyo 113-8655, Japan. makoto-ishi@umin.ac.jp
Joji Kitayama
Shoichi Kaizaki
Hiroshi Nakayama
Hironori Ishigami
Shin Fujii
Hiroyuki Suzuki
Tomomi Inoue
Akihiro Sako
Masahiro Asakage
Hiroharu Yamashita
Kenji Hatono
Hirokazu Nagawa
Development Bank of Japan · JPThe University of Tokyo · JPBank of Japan · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the clinical efficacy of Roux-en-Y reconstruction (RY) after distal gastrectomy, we compared postoperative outcomes of patients who underwent RY or conventional Billroth I reconstruction (B-I). A total of 50 patients were prospectively randomized to either B-I or RY reconstruction, and complications, postoperative course, and nutritional status were compared. Bile reflux and inflammation in the remnant stomach and lower esophagus were evaluated by postoperative follow-up endoscopy at 6 months. Operative time and blood loss as well as postoperative nutrition did not show significant differences between the two groups. As anticipated, 5 of 24 patients with RY reconstruction developed gastrojejunal stasis in the early postoperative period, which led to a longer postoperative hospital stay as compared with the B-I group (mean +/- S.D; B-I; 19.0 +/- 6.2, RY; 31.8 +/- 21.7 days) (P < 0.05). Endoscopic examination revealed that the frequency of bile reflux (P < 0.01) and degree of inflammation in the remnant stomach (P < 0.05) were less in the RY group than in the B-I group. However, inflammatory findings in the lower esophagus were observed in 7 (27%) of B-I, and 8 (35%) of the RY group, suggesting that late phase esophagitis was not improved in the RY group. Roux-en-Y reconstruction was effective in preventing duodenogastric reflux and resulting gastritis, but it did not prevent esophagitis. Because RY reconstruction induces the frequent complication of Roux-en-Y stasis, causing longer postoperative hospital stay, this method has limited advantages over B-I anastomosis after distal gastrectomy.

Indexed as

Anastomosis, SurgicalBlood Loss, SurgicalGastrectomyHumansLength of StayNutritional StatusProspective StudiesStomach NeoplasmsTreatment Outcome

Identifiers

PMID16240061
OpenAlexW2066647659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.