ArticleHistochemistry and cell biology2006
Vesicular glutamate transporter 1 immunoreactivity in extrinsic and intrinsic innervation of the rat esophagus.
Article in Histochemistry and cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Evidence That the Central Nervous System Can Induce a Modification at the Neuromuscular Junction That Contributes to the Maintenance of a Behavioral Response.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission.Cells · 2019Review
- Homer1 (VesL-1) in the rat esophagus: focus on myenteric plexus and neuromuscular junction.Histochemistry and cell biology · 2017Article
- Characterization of glutamatergic neurons in the rat atrial intrinsic cardiac ganglia that project to the cardiac ventricular wall.Neuroscience · 2016Article
- Morphology of P2X3-immunoreactive nerve endings in the rat laryngeal mucosa.Histochemistry and cell biology · 2016Article
- Localization of receptors for calcitonin-gene-related peptide to intraganglionic laminar endings of the mouse esophagus: peripheral interaction between vagal and spinal afferents?Histochemistry and cell biology · 2014Article
- VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review.ISRN neurology · 2013Review
- Morphology and chemical characteristics of subepithelial laminar nerve endings in the rat epiglottic mucosa.Histochemistry and cell biology · 2012Article
- Expression of vesicular glutamate transporters type 1 and 2 in sensory and autonomic neurons innervating the mouse colorectum.The Journal of comparative neurology · 2011Article
- Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors.American journal of physiology. Regulatory, integrative and comparative physiology · 2011Article
- Metabotropic glutamate receptors as novel therapeutic targets on visceral sensory pathways.Frontiers in neuroscience · 2011Article
- Distribution of P2X(3) receptor immunoreactivity in myenteric ganglia of the mouse esophagus.Histochemistry and cell biology · 2009Article
- VGluT2 expression in painful Achilles and patellar tendinosis: evidence of local glutamate release by tenocytes.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2008Article
- Vagal and hormonal gut-brain communication: from satiation to satisfaction.Neurogastroenterology and motility · 2008Review
- Recent progress in histochemistry.Histochemistry and cell biology · 2007Review
- The histochemistry and cell biology vade mecum: a review of 2005-2006.Histochemistry and cell biology · 2006Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Encouraged by the recent finding of vesicular glutamate transporter 2 (VGLUT2) immunoreactivity (-ir) in intraganglionic laminar endings (IGLEs) of the rat esophagus, we investigated also the distribution and co-localization patterns of VGLUT1. Confocal imaging revealed substantial co-localization of VGLUT1-ir with selective markers of IGLEs, i.e., calretinin and VGLUT2, indicating that IGLEs contain both VGLUT1 and VGLUT2 within their synaptic vesicles. Besides IGLEs, we found VGLUT1-ir in both cholinergic and nitrergic myenteric neuronal cell bodies, in fibers of the muscularis mucosae, and in esophageal motor endplates. Skeletal neuromuscular junctions, in contrast, showed no VGLUT1-ir. We also tested for probable co-localization of VGLUT1-ir with markers of extrinsic and intrinsic esophageal innervation and glia. Within the myenteric neuropil we found, besides co-localization of VGLUT1 and substance P, no further co-localization of VGLUT1-ir with any of these markers. In the muscularis mucosae some VGLUT1-ir fibers were shown to contain neuronal nitric oxide synthase (nNOS)-ir. VGLUT1-ir in esophageal motor endplates was partly co-localized with vesicular acetylcholine transporter (VAChT)/choline acetyltransferase (ChAT)-ir, but VGLUT1-ir was also demonstrated in separately terminating fibers at motor endplates co-localized neither with ChAT/VAChT-ir nor with nNOS-ir, suggesting a hitherto unknown glutamatergic enteric co-innervation. Thus, VGLUT1-ir was found in extrinsic as well as intrinsic innervation of the rat esophagus.
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