Evidence map›Paper›PMID 16227976›Full record

ReviewNature reviews. Molecular cell biology2005

FtsZ and the division of prokaryotic cells and organelles.

William Margolin

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 289 papers.

0numbers the graph read from it
0cells of the map it votes in
289citing papers in PubMed
14.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

289 citing papers in PubMed, 623 citations in OpenAlex.

  1. A lipid cue drives the subcellular localization of a self-inserting bacterial transmembrane protein.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  7. Cloneable contrast across all biological length scales.Journal of structural biology · 2026
    Article
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  9. Molecular structure of the ESCRT-III-based archaeal CdvAB cell division machinery.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Extensile Active Hydrogels Driven by Living FtsZ Polymers.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  11. Review
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  16. Bactericidal Activities of Nanoemulsion ContainingAntibiotics (Basel, Switzerland) · 2025
    Article
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  18. Review
  19. Article
  20. Article

229 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

William MargolinDepartment of Microbiology and Molecular Genetics, University of Texas Medical School, 6431 Fannin, Houston, Texas 77030, USA. William.Margolin@uth.tmc.edu

Funding

Targeting and assembly of E. coli division proteinsR01GM061074 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MARGOLIN, WILLIAM · 2000 to 2018
$5.7M
NIGMS NIH HHS R01 GM061074
6 · The paper itself

Abstract

Binary fission of many prokaryotes as well as some eukaryotic organelles depends on the FtsZ protein, which self-assembles into a membrane-associated ring structure early in the division process. FtsZ is homologous to tubulin, the building block of the microtubule cytoskeleton in eukaryotes. Recent advances in genomics and cell-imaging techniques have paved the way for the remarkable progress in our understanding of fission in bacteria and organelles.

Indexed as

Cell DivisionBacteriaBacterial Physiological PhenomenaBacterial ProteinsCytoskeletal ProteinsOrganellesBacterial ProteinsCytoskeletal ProteinsFtsZ protein, Bacteria

Identifiers

PMID16227976
PMCPMC4757588
OpenAlexW2081513604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.