ArticleProceedings of the National Academy of Sciences of the United States of America2005
D-type cyclins activate division in the root apex to promote seed germination in Arabidopsis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed, 179 citations in OpenAlex.
- Seed-specific overexpression of DREB2G alters seed morphology, oil accumulation, and germination in Arabidopsis.Plant cell reports · 2026Article
- Genome-scale transcriptome augmentation during Arabidopsis thaliana photomorphogenesis.Nature communications · 2025Article
- CrWRKY57 and CrABF3 cooperatively activateHorticulture research · 2025Article
- Establishment of single-cell transcriptional states during seed germination.Nature plants · 2024Article
- Arabidopsis Histone Variant H2A.X Functions in the DNA Damage-Coupling Abscisic Acid Signaling Pathway.International journal of molecular sciences · 2024Article
- Article
- Functional characterization of D-type cyclins involved in cell division in rice.BMC plant biology · 2024Article
- Seed longevity and genome damage.Bioscience reports · 2024Review
- Genome damage accumulated in seed ageing leads to plant genome instability and growth inhibition.The Biochemical journal · 2023Article
- The selection and application of peduncle length QTL QPL_6D.1 in modern wheat (Triticum aestivum L.) breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Protein Profiling ofPlants (Basel, Switzerland) · 2023Article
- Study on the interaction preference between CYCD subclass and CDK family members at the poplar genome level.Scientific reports · 2022Article
- The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development.The Plant cell · 2022Article
- Seed DNA damage responses promote germination and growth inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- The chromosome-level genome provides insight into the molecular mechanism underlying the tortuous-branch phenotype of Prunus mume.The New phytologist · 2022Article
- De novo transcriptome assembly of the cotyledon of Camellia oleifera for discovery of genes regulating seed germination.BMC plant biology · 2022Article
- Ectopic Expression of PoplarFrontiers in plant science · 2022Article
- Transcriptome-wide identification and characterization of microRNAs in diverse phases of wood formation in Populus trichocarpa.G3 (Bethesda, Md.) · 2021Article
- The DME demethylase regulates sporophyte gene expression, cell proliferation, differentiation, and meristem resurrection.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- OverexpressionInternational journal of molecular sciences · 2021Article
11 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seeds provide survival and dispersal capabilities by protecting the dormant mature plant embryo. Germination and resumption of development under favourable conditions requires the reinitiation of cell growth and division through poorly understood processes. Here we show that four phases of cell division activation during germination in Arabidopsis are related to external morphological changes. Cell division initiates in the root apical meristem (RAM) before root protrusion, followed by sequential activation of cell division in the cotyledons, shoot apical meristem (SAM), and secondary meristems. Major changes in transcript levels of >2,000 genes precede root emergence, including expression peaks of six D-type (CYCD) and two A-type cyclins. Two further CYCDs are activated later with the SAM. Early activated CYCDs play key roles in regulating the extent of cell division, because loss-of-function alleles of early CYCDs display reduced division activation and consequential delayed root emergence. Conversely, elevation of early CYCDs increases cell cycle activation in the RAM and promotes embryonic root (radicle) protrusion, whereas a later-acting CYCD does not. These phenotypes, together with their overlapping expression domains, support a cumulative action of a subset of CYCDs in cell cycle reactivation, rather than a complete functional redundancy. This analysis reveals a phenotype associated with loss-of-function of a plant cyclin and demonstrates that D-type cyclins regulate cell cycle reentry during meristem activation to promote successful germination and early seedling growth.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.