Evidence map›Paper›PMID 16222749›Full record

ArticleWorld journal of gastroenterology2005

Association between thyroid function and gallstone disease.

Henry Völzke, Daniel M Robinson, Ulrich John

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Co-Morbid Hypothyroidism and Liver Dysfunction: A Review.Clinical medicine insights. Endocrinology and diabetes · 2024
    Review
  6. Review
  7. Retrospective Evaluation of Gastrointestinal Signs in Hypothyroid Dogs.Animals : an open access journal from MDPI · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Thyroid hormone receptor β1 stimulatesJournal of lipid research · 2018
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Thyroid dysfunction and choleduocholithiasis.Middle East journal of digestive diseases · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Henry VölzkeInstitute of Epidemiology and Social Medicine, Ernst Moritz Arndt University, Greifswald, Germany. voelzke@uni-greifswald.de
Daniel M Robinson
Ulrich John
Universitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate those associations using data of the population-based Study of Health in Pomerania.

methodsA study population of 3 749 residents aged 20-79 years without previously diagnosed thyroid disease was available for analyses. Serum TSH was used to assess thyroid function. Cholelithiasis was defined by either a prior history of cholecystectomy or the presence of gallstones on ultrasound. Logistic regression was performed to analyze independent associations between thyroid function and cholelithiasis.

resultsThere were 385 persons (10.3%) with low (<0.3 mIU/L), 3 321 persons (88.6%) with normal and 43 persons (1.2%) with high serum TSH levels (>3 mIU/L). The proportion of cholelithiasis among males and females was 14.4% and 25.3%, respectively. Among males, there was an independent relation between high serum TSH and cholelithiasis (OR 3.77; 95%-CI 1.06-13.41; P<0.05). Also among males, there was a tendency towards an elevated risk of cholelithiasis in persons with low serum TSH (OR 1.40; 95%-CI 0.96-2.02; P = 0.07). In the female population, no such relation was identified.

conclusionThere is an association between thyroid and gallstone disease with a gender-specific relation between hypothyroidism and cholelithiasis.

Indexed as

AdultAgedCholelithiasisCross-Sectional StudiesFemaleGallstonesGermanyHumansMaleMiddle AgedThyroid Function TestsThyroid GlandThyrotropinThyrotropin

Identifiers

PMID16222749
PMCPMC4320366
OpenAlexW2152234732

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.