Evidence map›Paper›PMID 16220621›Full record

ArticleAccountability in research

Research on environmental health interventions: ethical problems and solutions.

David B Resnik, Darryl C Zeldin, Richard R Sharp

Abstract read
In one paragraph

Article in Accountability in research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. The paucity of ethical analysis in allergology.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2013
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David B ResnikNational Institute of Environmental Health Sciences, National Institutes of Health, P.O. Box 12233, Mail Drop NH 06, Research Triangle Park, NC 27709, USA. resnikd@niehs.nih.gov
Darryl C Zeldin
Richard R Sharp

Funding

Indoor Allergens And AsthmaZIAES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 2009 to 2025
$8.5M
INDOOR ALLERGENS AND ASTHMAZ01ES025041 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C · 1998 to 2008
$1.9M
Ethical, social, and legal issues in environmental health researchZIAES102646 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI RESNIK, DAVID · 2009 to 2025
$1.8M
Arachidonic Acid Metabolism By Murine CYP2C IsoformsZ01ES025044 · NIEHS · ENVIRONMENTAL HEALTH SCIENCES · PI ZELDIN, DARRYL C. · 2000 to 2004
–
Intramural NIH HHS ZIA ES102646
6 · The paper itself

Abstract

This article reviews a variety of ethical issues one must consider when conducting research on environmental health interventions on human subjects. The paper uses the Kennedy Krieger Institute lead abatement study as well as a hypothetical asthma study to discuss questions concerning benefits and risks, risk minimization, safety monitoring, the duty to warn, the duty to report, the use of control groups, informed consent, equitable subject selection, privacy, conflicts of interest, and community consultation. Research on environmental health interventions can make an important contribution to our understanding of human health and disease prevention, provided it is conducted in a manner that meets prevailing scientific, ethical, and legal standards for research on human subjects.

Indexed as

Environmental HealthAsthmaChildCommunity-Institutional RelationsConfidentialityConflict of InterestControl GroupsDisclosureHumansInformed ConsentNontherapeutic Human ExperimentationResearch DesignResearch SubjectsResearch Support as TopicRisk AssessmentVulnerable PopulationsBiomedical and Behavioral ResearchGrimes v. Kennedy Krieger Institute

Identifiers

PMID16220621
PMCPMC3941191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.