Evidence map›Paper›PMID 16220269›Full record

ArticleSkeletal radiology2006

Synovial sarcoma with radiological appearances of primitive neuroectodermal tumour/Ewing sarcoma: differentiation by molecular genetic studies.

P O'Donnell, T C Diss, J Whelan, A M Flanagan

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Skeletal radiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Article
  8. Genetic and molecular reappraisal of spindle cell adamantinoma of bone reveals a small subset of misclassified intraosseous synovial sarcoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019
    Article
  9. Review
  10. Article
  11. Intraosseous synovial sarcoma of the proximal tibia.International journal of surgical oncology · 2011
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

P O'DonnellDepartment of Radiology, Royal National Orthopaedic Hospital NHS Trust, Brockley Hill, Stanmore, Middlesex, UK. paul.o'donnell@rnoh.nhs.uk
T C Diss
J Whelan
A M Flanagan
University College Hospital · GBRoyal National Orthopaedic Hospital NHS Trust · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synovial sarcoma (SS) arises in soft tissues but may invade adjacent bone. We describe a case of SS presenting as aggressive lysis of the proximal ulna, the imaging of which suggested a primary bone lesion. Needle biopsy showed a "small round blue cell tumour", and a primitive neuroectodermal tumour (PNET)/Ewing sarcoma was suggested on the basis of the imaging appearances. The definitive diagnosis of synovial sarcoma was made following molecular genetic studies, which demonstrated a fusion product incorporating the genes SYT and SSX1. The importance of correct diagnosis to guide appropriate management, and, therefore, the necessity for molecular genetic studies, is discussed.

Indexed as

UlnaAdultBone NeoplasmsDiagnosis, DifferentialElbow JointHumansMaleNeoplasm ProteinsNeuroectodermal Tumors, PrimitiveProto-Oncogene ProteinsRadiographyRepressor ProteinsReverse Transcriptase Polymerase Chain ReactionSarcoma, SynovialNeoplasm ProteinsProto-Oncogene ProteinsRepressor ProteinsSS18 protein, humansynovial sarcoma X breakpoint proteins

Identifiers

PMID16220269
OpenAlexW1980563891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.