Evidence map›Paper›PMID 16219819›Full record

ArticleAJNR. American journal of neuroradiology2005

Brain compression without global neuronal loss in meningiomas: whole-brain proton MR spectroscopy report of 2 cases.

Benjamin A Cohen, Edmond A Knopp, Henry Rusinek, Songtao Liu, Oded Gonen

Open access · greenAbstract readCase Reports
In one paragraph

Article in AJNR. American journal of neuroradiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Surgical Resection of Non-Glial Tumors in the Motor Cortex.Brain tumor research and treatment · 2016
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Benjamin A CohenDepartment of Radiology, New York University School of Medicine, New York, NY 10016, USA.
Edmond A Knopp
Henry Rusinek
Songtao Liu
Oded Gonen
New York University · US

Funding

HIGHER SPEED, FIELD &SPATIAL RESOLUTION BRAIN 3D 1H MRSR01EB001015 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GONEN, ODED · 2002 to 2011
$5.8M
Quantifying Radiation-Therapy Brain Injury With 1H-MRSR21CA092547 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GONEN, ODED · 2002 to 2003
$422k
NCI NIH HHS CA92547NCI NIH HHS R21 CA092547NIBIB NIH HHS EB01015NIBIB NIH HHS R01 EB001015
6 · The paper itself

Abstract

We report the findings from whole-brain proton MR spectroscopy, quantifying the neuronal marker N-acetylaspartate (NAA), for 2 presurgical meningioma patients and 10 healthy controls. The patients' whole-brain NAA (WBNAA) concentrations were considerably elevated (3+ SDs) compared with healthy controls when excluding the tumors from brain volume; WBNAA levels normalized following correction to approximate "preneoplastic" brain size. These results suggest global neuronal preservation in these 2 patients while their brains were compressed by large, slowly growing, extra-axial masses.

Indexed as

Magnetic Resonance SpectroscopyBrainFemaleHumansMaleMeningeal NeoplasmsMeningiomaMiddle AgedNeuronsPressure

Identifiers

PMID16219819
PMCPMC7976145
OpenAlexW2136051980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.