ArticlePlant molecular biology2005
Modification of endogenous natural genes by gene targeting in rice and other higher plants.
Article in Plant molecular biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 77 citations in OpenAlex.
- Characterization of a new rice OsMADS1 null mutant generated by homologous recombination-mediated gene targeting.Planta · 2021Article
- Application of Genome Editing in Tomato Breeding: Mechanisms, Advances, and Prospects.International journal of molecular sciences · 2021Review
- Rice Gene Targeting by Homologous Recombination with Positive-Negative Selection Strategy.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Target-specific gene delivery in plant systems and their expression: Insights into recent developments.Journal of biosciences · 2020Review
- A review on advanced methods in plant gene targeting.Journal, genetic engineering & biotechnology · 2017Review
- New Biotechnological Tools for the Genetic Improvement of Major Woody Fruit Species.Frontiers in plant science · 2017Review
- Progress of targeted genome modification approaches in higher plants.Plant cell reports · 2016Review
- Review
- Biallelic Gene Targeting in Rice.Plant physiology · 2016Article
- The Regulatory Status of Genome-edited Crops.Plant biotechnology journal · 2016Review
- CRISPR-Cas9: Tool for Qualitative and Quantitative Plant Genome Editing.Frontiers in plant science · 2016Review
- Transcription Activator-Like Effector Nucleases (TALEN)-Mediated Targeted DNA Insertion in Potato Plants.Frontiers in plant science · 2016Article
- The MET1b gene encoding a maintenance DNA methyltransferase is indispensable for normal development in rice.Plant molecular biology · 2014Article
- Positive-negative-selection-mediated gene targeting in rice.Frontiers in plant science · 2014Review
- Identification of "safe harbor" loci in indica rice genome by harnessing the property of zinc-finger nucleases to induce DNA damage and repair.Frontiers in plant science · 2014Article
- ZFN-mediated gene targeting of the Arabidopsis protoporphyrinogen oxidase gene through Agrobacterium-mediated floral dip transformation.Plant biotechnology journal · 2013Article
- Targeted DNA excision in Arabidopsis by a re-engineered homing endonuclease.BMC biotechnology · 2012Article
- Using transgenic modulation of protein synthesis and accumulation to probe protein signaling networks in Arabidopsis thaliana.Plant signaling & behavior · 2011Review
- Mature seed-derived callus of the model indica rice variety Kasalath is highly competent in Agrobacterium-mediated transformation.Plant cell reports · 2010Article
- Site-specific integration of transgenes in soybean via recombinase-mediated DNA cassette exchange.Plant physiology · 2009Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The capability to modify a genomic sequence into a designed sequence is a powerful tool for biologists and breeders to elucidate the function of an individual gene and its cis-acting elements of multigene families in the genome. Gene targeting refers to the alteration of a specific DNA sequence in an endogenous gene at its original locus in the genome. In higher plants, however, the overwhelming occurrence of the random integration of transgenes by non-homologous end-joining is the main obstacle to develop efficient gene targeting. Two approaches have been undertaken to modify a genomic sequence in higher plants- chimeric RNA/DNA oligonucleotide-directed gene targeting to generate a site-specific base conversion, and homologous recombination-dependent gene targeting to produce either a base change or a gene replacement in a sequence-specific manner. The successful and reproducible targeting of an endogenous gene by homologous recombination, independently of gene-specific selection by employing a strong positive-negative selection, has been demonstrated for the first time in rice, an important staple food and a model plant for other cereal species. This review addresses the current status of targeting of an endogenous natural gene in rice and other higher plants and discusses possible models for Agrobacterium- mediated gene targeting by homologous recombination using a strong positive-negative selection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.