ReviewCurrent allergy and asthma reports2005
Pathogenesis of nasal polyps: an update.
Review in Current allergy and asthma reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Surgical interventions for chronic rhinosinusitis with nasal polyps.The Cochrane database of systematic reviews · 2014Pooled it
- Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps.The Cochrane database of systematic reviews · 2014Pooled it
- The clinical course of nasal polyps in relation with histological and radiological findings.Asia Pacific allergy · 2026Article
- Can SAPHO syndrome be combined with sinus swelling?Rheumatology advances in practice · 2026Article
- Angiomatous Nasal Polyps in a 43-Year-Old Female From North-Central Nigeria: A Case Report.Cureus · 2025Article
- Role of Nasal Fibroblasts in Airway Remodeling of Chronic Rhinosinusitis: The Modulating Functions Reexamined.International journal of molecular sciences · 2023Review
- The Role of Small Extracellular Vesicles and MicroRNAs in the Diagnosis and Treatment of Allergic Rhinitis and Nasal Polyps.Mediators of inflammation · 2022Review
- Effect of lipopolysaccharide and polyinosinic:polycytidylic acid in a murine model of nasal polyp.Scientific reports · 2021Article
- Association of MUC2, MUC5AC and MUC5B genes with the recurrence of nasal polyps.Experimental and therapeutic medicine · 2020Article
- Aberrant expression of miR-663 and transforming growth factor-β1 in nasal polyposis in children.Experimental and therapeutic medicine · 2018Article
- Eosinophil Chemokines and Clara Cell Protein 16 Production in Nasal Mucosa of Patients with Persistent Allergic Rhinitis.The Eurasian journal of medicine · 2017Article
- Glucocorticoids ameliorate TGF-β1-mediated epithelial-to-mesenchymal transition of airway epithelium through MAPK and Snail/Slug signaling pathways.Scientific reports · 2017Article
- Differential expression of tumor necrosis factor α, interleukin 1β, nuclear factor κB in nasal mucosa among chronic rhinosinusitis patients with and without polyps.Postepy dermatologii i alergologii · 2017Article
- A pilot study of symptom profiles from a polyp vs an eosinophilic-based classification of chronic rhinosinusitis.International forum of allergy & rhinology · 2016Article
- Significance of CYCLOOXYGENASE-2(COX-2), PERIOSTIN (POSTN) and INTERLEUKIN-4(IL-4) gene expression in the pathogenesis of chronic rhinosinusitis with nasal polyps.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015Article
- Surgical versus medical interventions in CRS and nasal polyps: comparative evidence between medical and surgical efficacy.Current allergy and asthma reports · 2015Review
- Chronic Rhinosinusitis and the Coagulation System.Allergy, asthma & immunology research · 2015Review
- Hypersensitivity to Aspirin and other NSAIDs: Diagnostic Approach in Patients with Chronic Rhinosinusitis.Current allergy and asthma reports · 2015Review
- Intercellular adhesion molecule-1 expression in activated eosinophils is associated with mucosal remodeling in nasal polyps.Molecular medicine reports · 2015Article
- Role of caffeic Acid on collagen production in nasal polyp-derived fibroblasts.Clinical and experimental otorhinolaryngology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cause of nasal polyp formation is still unknown. Genetic predisposition has been suggested, but there are scanty data to support such theories. Activated epithelial cells may be the major source of mediators inducing influx of inflammatory cells (mostly eosinophils) and proliferation and activation of fibroblasts leading to nasal polyp formation. Infectious agents (including viruses, bacteria, or fungi) may be potential primary factors activating nasal epithelial cells. Proinflammatory cytokines and growth factors play important roles in the persistence of mucosal inflammation associated with nasal polyps. Arachidonic acid metabolites seem to be particularly important in the pathogenesis of nasal polyps in patients with aspirin hypersensitivity rhinosinusitis/asthma syndrome.
Indexed as
Identifiers
16216171What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.