Evidence map›Paper›PMID 16208402›Full record

ArticleInternational journal of impotence research

Outcome analysis of sildenafil citrate for erectile dysfunction of Japanese patients.

K Kobayashi, S Hisasue, R Kato, T Shimizu, K Hashimoto, N Yamashita, N Itoh, T Tsukamoto

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Article in International journal of impotence research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

K KobayashiDepartment of Urology, Sapporo Medical University School of Medicine, Sapporo, Japan. kou@sapmed.ac.jp
S Hisasue
R Kato
T Shimizu
K Hashimoto
N Yamashita
N Itoh
T Tsukamoto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The approved maximal dose of sildenafil is only 50 mg in Japan, but the impact of dose regulation on treatment outcomes has not been established. Moreover, the contributors to the efficacy in patients having an intact peripheral nervous system have not been fully elucidated. We assessed in Japanese patients the treatment outcomes of sildenafil for erectile dysfunction (ED) under regulation of the approved dose and identified factors contributing to its efficacy among those with various etiologies other than pelvic surgery. We retrospectively reviewed 196 ED patients treated with sildenafil. The overall efficacy was 70.9% (139/196), and patients with psychological problems and concomitant cardiovascular disease showed high response rates (82.4 and 87.0%, respectively). Of the 139 responders, 89.9% achieved efficacy with a dose of 25 or 50 mg. Logistic regression analysis revealed concomitant cardiovascular disease and a favorable nocturnal penile tumescence result to be independent contributors to the efficacy.

Indexed as

AdultAgedAsian PeopleErectile DysfunctionHumansMaleMiddle AgedPiperazinesPurinesRetrospective StudiesSildenafil CitrateSulfonesTreatment OutcomePiperazinesPurinesSildenafil CitrateSulfones

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.