Evidence map›Paper›PMID 16208003›Full record

ArticleJournal of clinical microbiology2005

Oligonucleotide ligation assay for detection of mutations associated with reverse transcriptase and protease inhibitor resistance in non-B subtypes and recombinant forms of human immunodeficiency virus type 1.

Yolanda Vega, Lucía Pérez-Alvárez, Elena Delgado, Mercedes Muñoz, Gema Casado, Rocío Carmona, María Sierra, Elena Vázquez de Parga, Milagros Pinilla, Valentina García and 4 more

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Yolanda VegaArea de Patogenia Viral, Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Lucía Pérez-Alvárez
Elena Delgado
Mercedes Muñoz
Gema Casado
Rocío Carmona
María Sierra
Elena Vázquez de Parga
Milagros Pinilla
Valentina García
Leandro Medrano
Gerardo Contreras
Miguel Thomson
Rafael Nájera
Instituto de Salud Carlos III · ESCentro Nacional de Microbiologia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oligonucleotide ligation assay is a genotypic assay for the detection of resistance-associated mutations to reverse transcriptase and protease inhibitors in human immunodeficiency virus type 1 subtype B. This assay has been modified and developed for non-B subtypes and recombinant strains and has been evaluated with sequencing, resulting in a more sensitive assay than sequencing for non-B subtypes.

Indexed as

Point MutationAnti-HIV AgentsDNA LigasesDrug Resistance, ViralGene Products, polHIV-1HIV InfectionsHIV Protease InhibitorsHumansMicrobial Sensitivity TestsOligonucleotidesRecombination, GeneticReverse Transcriptase InhibitorsReverse Transcriptase Polymerase Chain ReactionRNA, ViralSensitivity and SpecificityAnti-HIV AgentsDNA LigasesGene Products, polHIV Protease InhibitorsOligonucleotidesReverse Transcriptase InhibitorsRNA, Viral

Identifiers

PMID16208003
PMCPMC1248433
OpenAlexW2151788443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.