Evidence map›Paper›PMID 16207990›Full record

ArticleJournal of clinical microbiology2005

Quality control and reference guidelines for CLSI broth microdilution susceptibility method (M 38-A document) for amphotericin B, itraconazole, posaconazole, and voriconazole.

A Espinel-Ingroff, A Fothergill, M Ghannoum, E Manavathu, L Ostrosky-Zeichner, M Pfaller, M Rinaldi, W Schell, T Walsh

Abstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Correlation ofAntimicrobial agents and chemotherapy · 2018
    Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. DMR040, a potential antifungal compound.The Journal of antibiotics · 2025
    Article
  7. Edeine BmBio · 2024
    Article
  8. Article
  9. Article
  10. Hyphae ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Plant Disease Control Efficacy ofPlants (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Article
  17. Biocontrol Potential ofFrontiers in microbiology · 2021
    Article
  18. Article
  19. Article
  20. Synthesis and characterization of NHThe Journal of antibiotics · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A Espinel-IngroffVCU Medical Center, Richmond, VA 23298-0049, USA. avingrof@hsc.vcu.edu
A Fothergill
M Ghannoum
E Manavathu
L Ostrosky-Zeichner
M Pfaller
M Rinaldi
W Schell
T Walsh

Funding

Treatment of Infections in Immunocompromised Children with Cancer, HematopoieticZ01SC006830 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI WALSH, THOMAS J. · 1996 to 2008
$5.8M
Treatment of Infections in Immunocompromised ChildrenZIASC006830 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI WALSH, THOMAS J. · 2009 to 2009
$2.4M
6 · The paper itself

Abstract

Although standard conditions are available for testing the susceptibilities of filamentous fungi to antifungal agents by the Clinical and Laboratory Standards Institute (CLSI; formerly National Committee for Clinical Laboratory Standards) broth microdilution assay, quality control (QC) MIC limits have not been established for any mold-agent combination. This multicenter (eight-center) study documented the reproducibility of tests for one isolate of Paecilomyces variotii ATCC MYA-3630 and 11 other mold isolates (three isolates of Aspergillus fumigatus; two isolates of A. terreus; one isolate each of A. flavus, A. nidulans, Fusarium moniliforme, and F. solani; and two isolates of Scedosporium apiospermum) by the CLSI reference broth microdilution method (M 38-A document). Control limits (amphotericin B, 1 to 4 microg/ml; itraconazole, 0.06 to 0.5 microg/ml; posaconazole, 0.03 to 0.25 microg/ml; voriconazole, 0.015 to 0.12 microg/ml) for the selected QC P. variotii ATCC MYA-3630 were established by the analysis of replicate MIC results. Reference isolates and corresponding MIC ranges were also established for 6 of the 12 molds evaluated. MIC limits were not proposed for the other five molds tested due to low testing reproducibility for these isolates.

Indexed as

Amphotericin BAntifungal AgentsDrug Resistance, FungalFungiHumansItraconazoleMicrobial Sensitivity TestsPaecilomycesPyrimidinesQuality ControlTriazolesVoriconazoleAmphotericin BAntifungal AgentsItraconazoleposaconazolePyrimidinesTriazolesVoriconazole

Identifiers

PMID16207990
PMCPMC1248457

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.