ArticleJournal of clinical microbiology2005
Characterization of new recombinant noroviruses.
Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Biological Specimen Banking as a Time Capsule to Explore the Temporal Dynamics of Norovirus Epidemiology.Viruses · 2023Article
- First Detection and Genomic Characterization of Bovine Norovirus from Yak.Pathogens (Basel, Switzerland) · 2022Article
- Prevalence and complete genome of bovine norovirus with novel VP1 genotype in calves in China.Scientific reports · 2019Article
- Recombinant GII.P16-GII.2 Norovirus, Taiwan, 2016.Emerging infectious diseases · 2017Article
- A novel feline norovirus in diarrheic cats.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016Article
- Etiology of Acute Diarrhea in Tunisian Children with Emphasis on Diarrheagenic Escherichia coli: Prevalence and Identification of E. coli Virulence Markers.Iranian journal of public health · 2014Article
- Evolutionary phylodynamics of Korean noroviruses reveals a novel GII.2/GII.10 recombination event.PloS one · 2014Article
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- Recombinant porcine norovirus identified from piglet with diarrhea.BMC veterinary research · 2012Article
- Norovirus genotypes in endemic acute gastroenteritis of infants and children in Finland between 1994 and 2007.Epidemiology and infection · 2012Article
- Updates on the genetic variations of norovirus in sporadic gastroenteritis in Chungnam Korea, 2009-2010.Virology journal · 2012Article
- Emergence of novel Norovirus recombinants with NVGII.1/NVGII.5 RdRp gene and NVGII.13 capsid gene among children and adults in Kolkata, India.International journal of molecular epidemiology and genetics · 2011Article
- Divergent evolution of norovirus GII/4 by genome recombination from May 2006 to February 2009 in Japan.Journal of virology · 2010Article
- Genetic heterogeneity and recombination in canine noroviruses.Journal of virology · 2009Article
- Prevalence and genotypes of human noroviruses in tropical urban surface waters and clinical samples in Singapore.Applied and environmental microbiology · 2009Article
- Predominance and circulation of enteric viruses in the region of Greater Cairo, Egypt.Journal of clinical microbiology · 2009Article
- Molecular epidemiology of norovirus gastroenteritis investigated using samples collected from children in Tunisia during a four-year period: detection of the norovirus variant GGII.4 Hunter as early as January 2003.Journal of clinical microbiology · 2009Article
- Genetic analysis of the capsid gene of genotype GII.2 noroviruses.Journal of virology · 2008Article
- Epidemic of genotype GII.2 noroviruses during spring 2004 in Osaka City, Japan.Journal of clinical microbiology · 2008Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noroviruses are important etiologic agents of acute gastroenteritis and show great genetic diversity. To characterize more fully previously detected strains that could not be assigned unequivocally to one particular genotype based on the RNA polymerase, we have sequenced a region in the capsid gene and, in some cases, in the junction between open reading frame 1 (ORF 1) and ORF 2. The results allowed us to identify several recombinant noroviruses: GGIIb viruses were detected for the first time in France in August 2000 and then spread through France and to Europe during the following winter. Here we present the characterization of three other probable GII recombinants which showed different phylogenetic positions depending on their ORF 1 and ORF 2 sequences. Analysis of the region located between ORF 1 and ORF 2 by a nucleotide identity window search showed a sudden shift in similarities. Moreover, recombination breakpoints were identified upstream and downstream of the beginning of ORF 2 by using a statistical test, thus confirming the involvement of this region in recombination. Unlike GGIIb, the three recombinants described here do not seem to have diffused widely in the community: one was found in a waterborne outbreak, and the other two were found in sporadic cases. Recombination is important for the evolution of RNA viruses and has already been described for noroviruses. Our results suggest that recombination is not a rare phenomenon among noroviruses, but not all these presumed recombinants that formed during RNA replication are able to spread widely.
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