Evidence map›Paper›PMID 16207347›Full record

ArticleArthritis research & therapy2005

Clinical and laboratory characteristics of drug-induced vasculitic syndromes.

Allan Wiik

Open access · goldAbstract readComment
In one paragraph

Article in Arthritis research & therapy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Drug-induced glomerular disease: attention required!Clinical journal of the American Society of Nephrology : CJASN · 2015
    Review
  6. Drug-induced glomerular disease: immune-mediated injury.Clinical journal of the American Society of Nephrology : CJASN · 2015
    Review
  7. The immunopathology of ANCA-associated vasculitis.Seminars in immunopathology · 2014
    Review
  8. Article
  9. Review
  10. The "other" vasculitis syndromes and kidney involvement.Pediatric nephrology (Berlin, Germany) · 2010
    Review
  11. Infection and vasculitis.Rheumatology (Oxford, England) · 2009
    Review
  12. Necrotizing vasculitis as a complication of propylthiouracil.The western journal of emergency medicine · 2008
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Allan WiikDepartment of Autoimmunology, Statens Serum Institut, Copenhagen, Denmark. aw@ssi.dk
Statens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical recognition of drug-induced vasculitic and lupus-like syndromes is very important because continued use of the offending drug can lead to irreversible and life-threatening vasculitic organ damage (e.g. end-stage renal disease or pulmonary haemorrhage). Withdrawal of the drug often leads to spontaneous recovery, meaning that immunosuppressive therapy can be avoided. The presence of myeloperoxidase-antineutrophil cytoplasmic antibodies, IgM anticardiolipin antibody, and antihistone antibodies in combination was found to be characteristic of drug-induced vasculitic syndromes caused by the antithyroid drugs propylthiouracil and methimazol. Clinically, skin vasculitis and arthralgias predominated and renal vasculitis was rare.

Indexed as

Acute Kidney InjuryAntibodies, AnticardiolipinAntibodies, Antineutrophil CytoplasmicAntithyroid AgentsAutoantibodiesAutoimmune DiseasesChurg-Strauss SyndromeDiagnosis, DifferentialGranulomatosis with PolyangiitisHumansImmunoglobulin MKidneyLupus Erythematosus, SystemicMethimazolePropylthiouracilSkinAntibodies, AnticardiolipinAntibodies, Antineutrophil CytoplasmicAntithyroid AgentsAutoantibodiesImmunoglobulin MMethimazolePropylthiouracil

Identifiers

PMID16207347
PMCPMC1257446
OpenAlexW1533508823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.