ArticleJournal of neuro-oncology2006
A report of a desmoplastic ganglioglioma in a 12-year-old girl with review of the literature.
Article in Journal of neuro-oncology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 35 citations in OpenAlex.
- Establishment and Characterization of Brain Cancer Primary Cell Cultures From Patients to Enable Phenotypic Screening for New Drugs.Frontiers in pharmacology · 2022Article
- Desmoplastic infantile astrocytoma and ganglioglioma: a series of 12 patients treated at a single institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Desmoplastic Infantile Ganglioglioma Masquerading as an Arachnoid Cyst.Oman medical journal · 2019Article
- Strong desmin expression in a congenital desmoplastic infantile ganglioglioma mimicking pleomorphic rhadomyosarcoma: a case report including ultrastructural and cytogenetic evaluation and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Desmoplastic non-infantile ganglioglioma in late adulthood.Journal of neuro-oncology · 2011Article
- Desmoplastic infantile astrocytoma with benign histological phenotype and multiple intracranial localizations at presentation.Journal of neuro-oncology · 2010Article
- Desmoplastic infantile and non-infantile ganglioglioma. Review of the literature.Neurosurgical review · 2010Review
- Desmoplastic infantile ganglioglioma: Report of a case and review of the literature.Journal of pediatric neurosciences · 2010Article
- A report of a desmoplastic non-infantile ganglioglioma in a 6-year-old boy with review of the literature.Neurosurgical review · 2009Article
- Imaging of desmoplastic infantile ganglioglioma: a spectroscopic viewpoint.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2009Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Desmoplastic infantile ganglioglioma is a supratentorial tumor that typically occurs in infants below the age of 24 months. Rare tumors with the same radiological and histological characteristics have been described in older subjects. We report a case of desmoplastic ganglioglioma in a 12-year-old girl with a 13 years follow-up. The patient presented with an inaugural generalized seizure. CT scan demonstrated a large superficial parieto-occipital mass, attached to the dura with solid and cystic components. Surgical resection was macroscopically complete. No adjuvant treatment was given. Thirteen years after surgery, the patient is symptom free. Histological examination revealed a pleomorphic tumor involving the meningeal space and the cortex. Meningeal portion was made of neoplastic astrocytes enmeshed in a dense network of connective tissue. The cortical component showed abnormal neurons, tumoral astrocytes and small foci of poorly differentiated cells with rare mitoses. Our observation and the seven others found in the literature indicate that desmoplastic gangliogliomas can occur in children and even in young adults. Despite some worrisome radiological and histological features, these tumors should not be misdiagnosed as malignant glioma. Like infantile cases, non-infantile desmoplastic gangliogliomas seem to have a favorable prognosis without additional therapy, if a total surgical resection can be performed.
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