Evidence map›Paper›PMID 16204575›Full record

ArticleApplied and environmental microbiology2005

Aquaporin expression and freeze tolerance in Candida albicans.

An Tanghe, Jennifer M Carbrey, Peter Agre, Johan M Thevelein, Patrick Van Dijck

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Into the Wild: A Look atJournal of fungi (Basel, Switzerland) · 2025
    Review
  4. Diverse Lineages ofGenetics · 2019
    Article
  5. Article
  6. Article
  7. Article
  8. Membrane properties of Enchytraeus albidus originating from contrasting environments: a comparative analysis.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2015
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

An TangheLaboratorium voor Moleculaire Celbiologie, Katholieke Universiteit Leuven, Kasteelpark Arenberg 31, B-3001 Leuven-Heverlee, Flanders, Belgium. An.Tanghe@bio.kuleuven.be
Jennifer M Carbrey
Peter Agre
Johan M Thevelein
Patrick Van Dijck
Vlaams Instituut voor Biotechnologie · BEJohns Hopkins Medicine · USJohns Hopkins University · USKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporins are members of the major intrinsic protein superfamily of integral membrane proteins which enable the transport of water, glycerol, and other solutes across membranes in various organisms. In microorganisms, the physiological role of aquaporins is not yet defined. We found a clear correlation between expression of the Candida albicans aquaporin-encoding gene AQY1 and freeze tolerance. A connection with the function for the aquaporin in the natural environment of C. albicans is, however, not obvious.

Indexed as

FreezingGene Expression Regulation, FungalAquaporinsCandida albicansFungal ProteinsGene DeletionPolymerase Chain ReactionSaccharomyces cerevisiae ProteinsAquaporinsAQY1 protein, S cerevisiaeFungal ProteinsSaccharomyces cerevisiae Proteins

Identifiers

PMID16204575
PMCPMC1265964
OpenAlexW2152483455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.