ArticleApplied and environmental microbiology2005
Factors influencing germination of Bacillus subtilis spores via activation of nutrient receptors by high pressure.
Article in Applied and environmental microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
37 citing papers in PubMed, 145 citations in OpenAlex.
- YpeB stability affects germination possibly through delaying SleB activity inJournal of bacteriology · 2026Article
- Combination of Medium-High-Hydrostatic-Pressure Treatment with Post-/Pre-Heat Treatment for Pasteurization ofMicroorganisms · 2025Article
- Effects of Aqua-Glycerol Uptake Facilitator Protein GlpF on Spore Germination ofFoods (Basel, Switzerland) · 2025Article
- Recent progress in proteins regulating the germination ofJournal of bacteriology · 2025Review
- Newly identified SpoVAF/FigP complex: the role inApplied and environmental microbiology · 2025Article
- Strategies for effective high pressure germination or inactivation ofApplied and environmental microbiology · 2024Article
- High-Pressure Inactivation ofFoods (Basel, Switzerland) · 2023Article
- Article
- Proteomic Response ofFoods (Basel, Switzerland) · 2022Article
- Heat Activation and Inactivation of Bacterial Spores: Is There an Overlap?Applied and environmental microbiology · 2022Article
- Moderate High-Pressure Superdormancy inApplied and environmental microbiology · 2022Article
- Suboptimal Bacillus licheniformis and Bacillus weihenstephanensis Spore Incubation Conditions Increase Heterogeneity of Spore Outgrowth Time.Applied and environmental microbiology · 2020Article
- Importance of Individual Germination Receptor Subunits in the Cooperative Function between GerA and Ynd.Journal of bacteriology · 2019Article
- Flow Cytometry Combined With Single Cell Sorting to Study Heterogeneous Germination ofFrontiers in microbiology · 2019Article
- Building of Pressure-Assisted Ultra-High Temperature System and Its Inactivation of Bacterial Spores.Frontiers in microbiology · 2019Article
- Effects of High Pressure on Bacillus licheniformis Spore Germination and Inactivation.Applied and environmental microbiology · 2017Article
- Analysis of Germination Capacity and Germinant Receptor (Sub)clusters of Genome-Sequenced Bacillus cereus Environmental Isolates and Model Strains.Applied and environmental microbiology · 2017Article
- Effects of High-Pressure Treatment on Spores of Clostridium Species.Applied and environmental microbiology · 2016Article
- Investigating the Inactivation Mechanism of Bacillus subtilis Spores by High Pressure CO2.Frontiers in microbiology · 2016Article
- The effects of heat activation on Bacillus spore germination, with nutrients or under high pressure, with or without various germination proteins.Applied and environmental microbiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Different nutrient receptors varied in triggering germination of Bacillus subtilis spores with a pressure of 150 MPa, the GerA receptor being more responsive than the GerB receptor and even more responsive than the GerK receptor. This hierarchy in receptor responsiveness to pressure was the same as receptor responsiveness to a mixture of nutrients. The levels of nutrient receptors influenced rates of pressure germination, since the GerA receptor is more abundant than the GerB receptor and elevated levels of individual receptors increased spore germination by 150 MPa of pressure. However, GerB receptor variants with relaxed specificity for nutrient germinants responded as well as the GerA receptor to this pressure. Spores lacking dipicolinic acid did not germinate with this pressure, and pressure activation of the GerA receptor required covalent addition of diacylglycerol. However, pressure activation of the GerB and GerK receptors displayed only a partial (GerB) or no (GerK) diacylglycerylation requirement. These effects of receptor diacylglycerylation on pressure germination are similar to those on nutrient germination. Wild-type spores prepared at higher temperatures germinated more rapidly with a pressure of 150 MPa than spores prepared at lower temperatures; this was also true for spores with only one receptor, but receptor levels did not increase in spores made at higher temperatures. Changes in inner membrane unsaturated fatty acid levels, lethal treatment with oxidizing agents, or exposure to chemicals that inhibit nutrient germination had no major effect on spore germination by 150 MPa of pressure, except for strong inhibition by HgCl2.
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